Biomedical Sciences - PRINCIPLES OF DISEASE

Undergraduate Week 9

Lecture outline

The first lecture will describe some of the common causes and mechanisms of carcinogenesis and will explain the importance of specific genetic alterations such as proto-oncogene activation and tumour suppressor gene inactivation in the evolution of cancer. The second lecture looks at the early stages of neoplasia, such as dysplasia, and how the recognition of early stages can be important in cancer screening.