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Teaching

Leeds Tuesday Teaching :: Set 3 - Advanced B cell lymphomas






Case 1

Male 40 years

Polypoidal mass at the D-J flexture with normal surrounding duodenal jejunal mucosa.




H&E 481153


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CD20 481154


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Bcl-6 481155


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Ki67 (MIB-1) 481156


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CD23 481157


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CD03 481158


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CD10 481159


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BCL-2 481160


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Case 2

Female 60 years

Renal pelvic tumour. Abdominal lymph node.




H&E 481161


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CD20 481162


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BCL-2 481163


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CD10 481164


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Bcl-6 481165


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CD03 481167


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Ki67 (MIB-1) 481168


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IgD 481484


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Case 3

Male 40 years

Enlarged groin lymph node.




H&E 483377


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CD03 483360


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BCL-2 483362


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Ki67 (MIB-1) 483363


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CD10 483365


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CD23 483368


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CD20 483374


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IRF4 483375


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Bcl-6 483376


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Case 4

Female 36 years

Bilateral cervical lymphadenopathy and lesion base of tongue. Biopsy from the latter. FISH has shown IGH- MYC, BCL2 and BCL6 rearrangements.




H&E 481178


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CD03 481179


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CD20 481180


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CD10 481181


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Bcl-6 481182


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BCL-2 481183


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IRF4 481184


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Ki67 (MIB-1) 481185


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Case 5

Male 20 years

Unwell. Omental lesions. Abdominal nodule.




H&E 481186


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BCL-2 481187


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CD10 481188


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MYC 481189


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CD03 481190


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CD20 481191


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Ki67 (MIB-1) 481192


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Bcl-6 481193


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Case 6

Female 80 years

Chest flat and red lesions.




H&E 481487


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CD20 481490


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Bcl-6 481492


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CD34 481598


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Ki67 (MIB-1) 481195


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CD10 481196


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IRF4 481198


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BCL-2 481199


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CD03 481202


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CD05 481203


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Case 7

Male 50 years

Suspicious neck lymphadenopathy with malaise and weight loss.




H&E 481204


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OCT-2 481205


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CD20 481206


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CD03 481207


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PD-1 481208


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IRF4 481209


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CD21 481210


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CD10 481211


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Bcl-6 481212


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IgD 481213


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CD79 481214


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PAX5 481215


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Case 8

Male 20 years

Weight loss and night sweats. Extensive lymphadenopathy.




H&E 481216


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PAX5 481217


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CD15 481218


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CD05 481219


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CD07 481220


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CD03 481221


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CD08 481222


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481223


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CD20 481224


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CD79 481225


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LMP1 Latent membrane protein 1 481226


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OCT-2 481227


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CD30 481228


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CD04 481229


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IRF4 481230


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CD02 481231


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Case 9

Male 28 years

Multiple neck nodes, mediastinal mass and lung mass. Wedge excision.




H&E 481232


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CD30 481233


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CD03 481234


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CD20 481235


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CD15 481236


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PAX5 481237


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IRF4 481238


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LMP1 Latent membrane protein 1 481239


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ALK-1 481240


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Case 10

Male 70 years

Perforated bowel. NET present, but an ulcerated anaplastic focus is also noted.




H&E 481241


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IRF4 481242


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PAX5 481243


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CD30 481244


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LMP1 Latent membrane protein 1 481245


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CD15 481246


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ALK-1 481247


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OCT-2 481248


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CD45 481249


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CD02 481250


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Ki67 (MIB-1) 481251


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CD03 481252


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CD20 481253


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CD79 481254


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Case 11

Male 50 years

Bilateral adrenal masses. Clinical impression is tuberculosis. Adrenal excision.




H&E 481255


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CD20 481257


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CD30 481259


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CD03 481261


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Bcl-6 481262


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CD10 481263


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LMP1 Latent membrane protein 1 481266


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IRF4 481270


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Ki67 (MIB-1) 481272


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Case 12

Female 60 years

istory of inflammatory bowel disease on azathioprine, multiple lung nodules on CT and rectal ulceration.




H&E 481494


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LMP1 Latent membrane protein 1 481495


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CD03 481496


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CD30 481277


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Ki67 (MIB-1) 481278


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IRF4 481280


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CD79 481284


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CD20 481282


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Case 13

Male 60 years

Asymmetrical tonsils removed for histology.




H&E 481285


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CD138 481286


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CD20 481287


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LMP1 Latent membrane protein 1 481289


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CD03 481290


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CD30 481291


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IRF4 481292


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ALK-1 481293


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PAX5 481294


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481295


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CD79 481296


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CD45 481297


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Ki67 (MIB-1) 481303


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Case 14

Male 40 years

Suspicious lesion in post-nasal space HIV+ve.




H&E 481308


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Ki67 (MIB-1) 481311


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CD30 481312


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CD79 481315


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CD03 481321


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CD45 481323


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CD138 481326


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Cyclin. D1 481328


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CD20 481331


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LMP1 Latent membrane protein 1 481334


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CD56 481336


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IRF4 481497


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481499


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CD319 481501


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Case 15

Female 50 years

Lung nodule. No evidence of lymphoma or plasma cell dyscrasia.




H&E 481352


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Lambda 481365


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CD03 481380


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CD20 481387


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CD19 481392


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CD138 481502


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Kappa 481504


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IRF4 481505


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Congo Red 484464


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