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Teaching

British Society of Haematology (BSH) meeting 2023






Case 1

Female 55 years

Presented with fever and feeling unwell. Hb 97g/L, WCC 4.3 x 10-9, plt 30 x 10-9/L. Slide 542227.svs - bone marrow aspirate or aspirate.




542227


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H&E 542223


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CD34 542224


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C-KIT (CD117) 542225


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CD25 542226


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Reticulin 542288


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Case 2

Male 62 years

Previously fit and well. Presented with recurrent infections, rash and pancytopenia. Hb 102g/L, WCC 3.2 x10-9, plt 84 x 10-9/L. Slide 542229.svs - aspirate.




542229


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H&E 542228


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Case 3

Male age unknown

Finnish/Jamaican baby boy, normal pregnancy. Had prolonged neonatal jaundice requiring phototherapy. presented to A&E after feeling unwell for 2 weeks. Hb 39g/L, WCC 44 x10-9, plt 436 x 10-9/L. Slide 542230.svs - peripheral blood.




542230


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Case 4

Male 56 years

Presents with fatigue and nose bleeds. Hb 158g/L, WCC 4.3 x 10-9, neutrophils 0.1, plt 85 x 10-9/L. Slide 542232.svs - aspirate.




542232


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H&E 542231


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Case 5

Male 75 years

Presents with a 6 month history of polyuria, polydipsia, weight loss. CT scan shows pulmonary fibrosis, hydronephrosis and small volume. Slide 542233.svs - aspirate.




542233


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H&E 542234


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Reticulin 542235


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CD68 542236


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S100 542237


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CD163 542238


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CD01a 542239


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CD207 (Langerin) 542289


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Case 6

Male 31 years

Previous treated managed as ITP. Hb 115g/L, WCC 2.7 x 10-9, plt 107 x 10-9/L. Presented with back pain. MRI showed diffuse marrow uptake and splenomegaly. Slide 542240.svs - peripheral blood.




542240


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Case 7

Female 71 years

Presented with fatigue, lethargy and weight loss. She noticed painless lymphadenopathy. Hb 76g/L, WCC 2.3 x10-9, plt 36 x 10-9/L.




H&E 542241


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Reticulin 542242


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CD30 542243


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PAX5 542244


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IRF4 542245


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LMP1 Latent membrane protein 1 542246


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CD20 542247


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Case 8

Female 52 years

Previously fit and well, presented feeling unwell and with bleeding. Hb 106g/L, WCC 5.2 x 10-9, neutrophils 0.47, plt 98 x 10-9/L. Slide 542249.svs - aspirate.




542249


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H&E 542250


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CD34 542251


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CD79 542252


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CD19 542253


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CD10 542254


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Terminaldeoxynucleotidyl transferase (TdT) 542255


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CD33 542256


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CD13 542257


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CD99 542258


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C-KIT (CD117) 542248


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