Female 54 years

History of abdominal pain and haematuria. Clinically considered to be renal colic. CT showed a lesion in the lower pole of the left kidney - ? perinephric abscess ? tumour. Past history of oophorectomy (1990). Laproscopic nephrectomy performed.



Specimen: Left kidney.

Macro: Specimen comprises of kidney weighing 210g and measuring 135mm (S-I) x 73mm (side to side) x 62mm (A-D). Staples are present in the hilar area. Cut sections show a pale well circumscribed but not encapsulated tumour involving the lower pole of the kidney measuring up to 45mm in maximal dimension. The tumour has a central area of haemorrhage, which appears slightly softened. The tumour appears to extend to the tip of the lower pole but does not appear to extend in to the adjacent perinephric fat. The adrenal gland is not present with the specimen.

Immunohistochemistry:
Positive for: Actin, desmin, HMB-45 and Melan-A.

Female 64 years

Very small ? pap growth 2-3 mm in diameter with ? benign, ? low grade. ?TCC.



Specimen: Bladder biopsy.

Macro: 1 piece plus fragments 3 mm.

Immunohistochemistry:
Not done.

Male 34 years

Right renal mass.



Specimen: Partial nephrectomy.

Macro: Specimen received in two parts, including a 20x15x15mm nodule with a tan cut surface and a disc of renal parenchyma measuring 35x35x10mm which contained a round central defect 15mm in diameter.

Immunohistochemistry:
CD117 diffuse membranous positivity, CK7 and CD10 patchy positivity; RCC and vimentin negative.

Male 22 years

Left orchidectomy for maldescended testis.



Specimen: Testis.

Macro: Testis 3 x 1.8 x 1.8 cm with 2cm spermatic cord. No focal lesions identified.

Immunohistochemistry:
Not performed.

Male 67 years

Left laparoscopic radical nephrectomy for tumour.



Specimen: Kidney.

Macro: Left kidney 130x70x40mm with ureter 20mm and surrounding fat up to 70mm. In the superior aspect of the specimen, within the fat but separate from the kidney is a mass 90x70x60mm.

Immunohistochemistry:
WT1 positive. Vimentin, CD10, CK7 and CD117 negative.

Female 78 years

Left kidney. Left simple nephrectomy with stone in renal pelvis with abscess. Prev psoas abscess.



Specimen: Kidney.

Macro: Kidney 16 x 9 x 6 cm. Slicing shows small kidney, atrophic, inflammation/necrosis and fat necrosis. No definite tumour seen. No stones noted.

Immunohistochemistry:
NONE; BUT SPECIAL STAINS e.g ZN, DPAS, GROCOTT'S - all negative.

Female 38 years

Solid bladder tumour.



Specimen: Bladder.

Macro: Bladder tissue, approx 4g.

Immunohistochemistry:
None.

Female 59 years

Right kidney mass suspicious for RCC. Right nephrectomy.



Specimen: Right kidney.

Macro: Circumscribed tumour in upper pole 3.0 x 2.5 x 2.0cm composed of pale and yellow crumbly and haemorrhagic tissue. No gross vascular or sinus invasion and confined to the kidney.

Immunohistochemistry:
TFE 3 staining positive.

Male 62 years

Phimosis.



Specimen: Foreskin.

Macro: None.

Immunohistochemistry:
N/A.

Male 64 years

Solid tumour on base and left wall, unusual cobblestone appearance, relatively avascular.



Specimen: Bladder tumour resection.

Macro: 8 grams of bladder chippings.

Immunohistochemistry:
CK7+ CK20+ CEA+ PSA.

Male 70 years

Exophytic RCC left lower pole. Partial nephrectomy.



Specimen: Partial nephrectomy.

Macro: Piece of renal tissue measuring 46 x 41 x 21 mm. On slicing, the tissue contains a partly cystic and partly solid tumour measuring up to 27 x 20 x 25 mm, which is well-circumscribed.

Immunohistochemistry:
CK 7 positive, high molecular weight cytokeratin positive, RCC marker negative, CD10 negative, AMACR negative.

Male 72 years

Malignant groin node.Abnormal distal urethra and glans penis. ?Urethral squamous cell carcinoma.



Specimen: Partial penectomy.

Macro: 16mm tumour in glans.

Immunohistochemistry:
P16 - supplied. CK7 positive. Negative for GATA3, CK20.

Male 67 years

PSA 9.



Specimen: Prostate Needle Biopsy.

Macro: 2 cores.

Immunohistochemistry:
None.

Male 61 years

PSA 5.8. Lesion left base on MRI PIRADS 4.



Specimen: TRUS prostate biopsies right base.

Macro: 2 cores longest 2 cm.

Immunohistochemistry:
Prostate triple-stain (34BE12, p63 = brown and AMACR = red).

Male 60 years

PSA 9.2. Biopsy 2017 HGPIN.



Specimen: prostate core biopsy.

Macro: core biopsy.

Immunohistochemistry:
None performed.

Male 65 years

Follow up biopsy on active surveillance.



Specimen: Prostate core.

Macro: Core biopsy.

Immunohistochemistry:
HMWCK - provided.

Female 79 years

Solid urinary bladder mass.



Specimen: TURB specimen.

Macro: TURBT.

Immunohistochemistry:
None.

Male 34 years

Left testis.



Specimen: Left orchidectomy.

Macro: Left testis - solid testicular mass (40mm). Positive for CD117 Negative for OCT4, PLAP, CD45.