Male 6 years

Phimosis.



Specimen: Foreskin.

Macro: Foreskin.

Immunohistochemistry:
None.

Male 45 years

Testicular cancer.



Specimen: Right transinguinal orchidectomy.

Macro: Multilobulated soft to firm cream tumour with focal hemorrhagic areas 5.4 x 5.5 x 3.5cm. Appears confined to testis.

Immunohistochemistry:
C-kit provided. Oct4, CD30, MNF116 and PLAP negative.

Male 25 years

Urine -ve.



Specimen: TURBT.

Macro: Multiple fragments of light brown tissue together weighing 0.5g, in aggregate measuring 15 x 15 x 3mm. AE in A1.

Immunohistochemistry:
None.

Male 52 years

?Left testicular cancer. Tumour markers sent. 2cm lump on ultrasound.



Specimen: Testis.

Macro: Testis weighs 50g. Testis including spermatic cord measures 110 x 40 x 30mm. The testis itself measures 38 x 30 x 30mm with attached spermatic cord 60 x 20 x 15mm. Within the mid portion of the testis is a very well circumscribed mixed cystic/solid cream-coloured lesion measuring 18 x 16 mm.

Immunohistochemistry:
None.

Female 51 years

Solid bladder tumour resected to muscle.



Specimen: Bladder Chips.

Macro: 30g of tissue.

Immunohistochemistry:
Pan cytokeratin positive.

Male 53 years

8mm non-changing but vascular left testicular lesion on U/S. ? tumour.



Specimen: Left testis.

Macro: Testis with spermatic cord, 90mm long. The testis, 50x35x35mm, is surrounded by a small hydrocoele with smooth tunica vaginalis. On slicing, there is a parahilar tumour, 7mm in diameter which has a solid dark brown cut surface and is confined to the testis.

Immunohistochemistry:
nil.

Male 56 years

Solid bladder tumour.



Specimen: TURBT.

Macro: BLADDER TUMOUR | Multiple fragments of brown tissue together weighing 4g and in aggregate | measuring 45 x 45 x 5mm. AE in A1-A2.

Immunohistochemistry:
The tumour cells are immunoreactive for S100, CD56, Chromogranin and Synaptophysin whilst they are negative for CK7 AND CK20.

Male 62 years

Upper pole right kidney ?RCC.



Specimen: Right partial nephrectomy.

Macro: 77g partial nephrectomy, 4 x 2.5 x 2cm. Parenchymal margin inked black. On sectioning 1.4cm circumscribed whitish tumour, 0.2cm from the nearest parenchymal margin.

Immunohistochemistry:
None performed.

Male 70 years

Bladder tumour and mesenteric nodules.



Specimen: Palliative cystoprostatectomy.

Macro: The bladder wall is thickened by firm pale tumour up to a thickness of approximately 25 mm. Firm irregular tumour extends into surrounding fatty tissue at the anterosuperior aspect of the specimen for a distance of up to 45 mm.

Immunohistochemistry:
CK7+, CK20-, EMA+, E-cadherin+

Male 50 years

Right testicular tumour with raised LDH.



Specimen: Orchidectomy.

Macro: Gray white homogenous firm nodule in the lower pole of testis pushing the epididymis.

Immunohistochemistry:
Calretinin and vimentin positive.

Male 44 years

Right renal mass.



Specimen: Right partial nephrectomy.

Macro: 55mm multicystic lesion containing mucoid material.

Immunohistochemistry:
None ***Note - Please base diagnosis on assumption other blocks showed similar features***.

Male 82 years

Radical orchidectomy ? tumour (pt had previous G3 TCC of bladder treated with BCG, although this information was not given to the pathologist).



Specimen: Radical orchidectomy specimen.

Macro: Enlarged testis measuring 60 x 45 x 30mm. Intact capsule. Small hydrocele present. Cut surface shows a cream coloured lesion 24mm.

Immunohistochemistry:
Special stains ZN and PAS negative.

Male 76 years

PSA 17. Volume 34cc.



Specimen: TRUS Bx.

Macro: Two cores 13 and 12mm.

Immunohistochemistry:
No.

Male 75 years

PSA not stated, template biopsies.



Specimen: Prostate cores.

Macro: Prostate core.

Immunohistochemistry:
None.

Male 74 years

PSA 9.2. Gleason score 3 + 3 prostate cancer on AS. Repeated template biopsies.



Specimen: Core biopsies from right apex posterior.

Macro: Right Apex posterior.

Immunohistochemistry:
Racemase (red), p63/34BE12 cocktail.