Male 41 years

Right renal mass.



Specimen: right kidney.

Macro: solid cream, tumour 7mm in maximum dimension in the upper pole.

Immunohistochemistry:
not done.

Male 82 years

Previous history of amyloidosis ?recurrence.



Specimen: TURBT.

Macro: TURBT weighing 5 grams.

Immunohistochemistry:
SAA,TTR, K/L- All negative, Congo red positive with apple green birefringence on polarised light.

Male 39 years

US reveal mass in left testicle, sinister lesion could not be excluded, tumour markers normal, radical left inguinal orchiectomy.



Specimen: Unilateral left radical orchiectomy (left testicle and cord).

Macro: A testicle with spermatic cord weighing 29g. It is 100mm in length with testis 40x28x23mm. The tunica is intact. On slicing through the testis there is a well-demarcated ovoid mass 12mm, with variable creamy and haemorrhagic cut surface. The tumour abuts the tunica which appears thickened in this area. The rest of the testis is normal.

Immunohistochemistry:
Immunohistochemistry shows the tumour cells are positive for CD30, AE1/AE3 and podoplanin (D2-40). The tumour cells are negative for EMA and CD117.

Male 74 years

Enlarged prostate, history of retention of urine.



Specimen: TURP.

Macro: Multiple chips together 8grams. All processed.

Immunohistochemistry:
Provided: CK7, NKX3.1, S100, GATA3, PIN cocktail.

Male 80 years

Robotic assisted laparoscopic nephrectomy for distal ureteric TCC********SUPPLEMENTARY QUESTION********.



Specimen: left nephroureterectomy.

Macro: Kidney with attached ureter weighing 400g. Ureter distended distally over 50mm. renal pelvis dilated.

Immunohistochemistry:
N/A.

Male 46 years

Bosniak III-IV cyst in left kidney.



Specimen: Left kidney.

Macro: 65 x 50 x 55mm multicystic encapsulated left kidney tumour. No solid areas identified macroscopically.

Immunohistochemistry:
None.

Male 52 years

Haematuria, very tight urethral stricture, 2cm polyp bladder neck with visually some component of papillary structures; unable to resect due to small scope; biopsies taken and ablated to base.



Specimen: Bladder lesion.

Macro: Three cream fragments 6, 5 and 7mm maximum dimension. No reserve.

Immunohistochemistry:
None performed.

Male 37 years

Known seminoma; 5mm lesion left testis.



Specimen: Left testis.

Macro: Testis 32x20x17mm with an ill defined 8mm pale lesion.

Immunohistochemistry:
n/a.

Female 38 years

5.5cm right renal upper pole tumour.



Specimen: Nephrectomy.

Macro: Nephrectomy specimen showing a well defined tumour which is cystic, multiloculated containing clear serous fluid. The cyst wall are smooth and shiny. Some soft scanty solid areas with no necrosis or haemorrhage.

Immunohistochemistry:
Stromal component positive for SMA, Desmin, ER, PR, CD10. Epithelial component reactive for PAX8.

Male 56 years

PSA 6.6, T2 N0 M0, GG2********SUPPLEMENTARY QUESTION********.



Specimen: Prostate.

Macro: Robotic radical prostatectomy. Specimen from right seminal vesicle and vas.

Immunohistochemistry:
Nil.

Male 38 years

Previous injection of silicone 10 years ago into penis. Inflammatory reaction. Removal of foreign body and skin.



Specimen: Excision of penile skin.

Macro: An ellipse of penile skin measuring 50x20x10mm. The specimen is not orientated. Sectioning shows the cut surface is pale and firm throughout. No focal lesions are seen.

Immunohistochemistry:
None.

Male 52 years

Longstanding testicular mass, recent increase in size. Normal serum tumour markers.



Specimen: Orchidectomy.

Macro: Heterogenous, solid white tumour replacing entire testicle.

Immunohistochemistry:
Positive for panCK, chromogranin, CD56 and synaptophysin. Inhibin, OCT4, PLAP, Glypican3 negative.

Male 76 years

PSA11.6.



Specimen: Prostate core biopsy.

Macro: Three core biopsies measuring between 12 and 15mm. AE.

Immunohistochemistry:
N/A.

Male 74 years

47cc, PSA 8, R anterior gland P4.



Specimen: Biopsy from right apex.

Macro: Tissue core 15 mm in length.

Immunohistochemistry:
combined HMWCK (34BE12) and racemase submitted.

Male 66 years

Known GL 3+3. PSA 5.5. No change on MRI - Biopsy for clarity as spinal lesion found T12 under CUP also.



Specimen: Prostate TEMPLATE Biopsy- right anterior.

Macro: 2 needle cores of grey white tissue.

Immunohistochemistry:
None.