Male 49 years

Right kidney tumour.



Specimen: Right partial nephrectomy.

Macro: A wedge of kidney measuring 35x30x25mm. The surgical resection is inked red and the opposite is inked black. The renal capsule also contains attached perinephric fat. On serial slicing, a yellowish solid tumour is identified measuring approximately 25x18x13mm. The tumour is just 1mm from the inked red margin. All submitted.

Immunohistochemistry:
Not performed.

Female 85 years

Bladder tumour. History of kidney tumour.



Specimen: TURBT.

Macro: Multiple pieces.

Immunohistochemistry:
CK7 and PAX8 positive. p63, GATA3 and Chromogranin negative.

Male 64 years

L renal tumour with LN enlargement, suspected RCC.



Specimen: Left kidney.

Macro: Kidney 145 x 120 x 110 mm with nodular pale tumour with whorled cut surface, 140 mm maximum. Tumour centred on renal hilum and compresses renal parenchyma without definite parenchymal invasion. Tumour present in renal blood vessels. Small foci of necrosis. Normal ureter and adrenal. No lymph nodes present.

Immunohistochemistry:
AE1-AE3 and desmin included.

Male 33 years

Orchidectomy.



Specimen: Orchidectomy.

Macro: Radical orchidectomy specimen 68x50x46mm. On the sectioning there is grey solid tumour measuring 44mm in greatest diameter and it is limited to the testis.

Immunohistochemistry:
The tumour cells express SALL-4. Expressions of Oct3/4 and PLAP are not present in tumour cells and in the seminiferous tubules.

Male 81 years

New diagnosis solid bladder tumour. *****SUPPLEMENTARY QUESTION********



Specimen: TURBT.

Macro: Bladder tumour weighing 21.9g.

Immunohistochemistry:
CAM5.2, Ki67, Synaptophysin, PSA, CD56, Gata-3, CK5/6 included.

Male 65 years

Presented with haematuria and anaemia.CT abdomen showed renal mass. *****SUPPLEMENTARY QUESTION********



Specimen: Nephroureterectomy.

Macro: 30x25x25 mm, relatively well circumscribed, soft brown tumour, no extension to renal vein.

Immunohistochemistry:
CD117+, CK7+, PAX8 +, CD10 -, Vimentin - GATA3 -.

Female 89 years

Bladder biopsy. Previous TCC 2014, 2017 and 2017 ?recurrence.



Specimen: Bladder biopsy.

Macro: Multiple fragments of cream tissue measuring in aggregate 20 x 15 x 6mm.

Immunohistochemistry:
None.

Male 60 years

Enlarged left testis. No recent trips abroad.



Specimen: Left testis.

Macro: Left testis and spermatic cord. The testis was enlarged and measured 50 x 40 x 20 mm. Bivalving the testis revealed a tan cut surface in which there were grey mottled areas.

Immunohistochemistry:
Oct 3/4, PLAP and MNF116 Negative. ZN and PAS-D Negative.

Male 42 years

Patient of African origin presenting with haematuria. On imaging has metastatic disease.



Specimen: Right nephrectomy.

Macro: The tumour measures 100mm and appears as a solid tan to white coloured well-defined lobulated tumour, with focal myxoid and cystic areas. There is invasion of renal sinus fat.

Immunohistochemistry:
Positive for PAX8, CK7, CAM 5.2, CEA and vimentin. There is focal positivity for OCT3/4, 34BetaE12 and p63. Tumour cells are negative for CK20, GATA3 and Racemase.

Male 38 years

? tumour left testicle. Tumour markers normal. Left radical orchidectomy.



Specimen: Left radical orchidectomy.

Macro: 10x9x8mm firm white solid mass inferior aspect of testis.

Immunohistochemistry:
AE1/3, calretinin, WT1, D240 positive. Oct4 negative.

Male 54 years

Phimosis, penile warts on foreskin.



Specimen: Foreskin.

Macro: Wrinkled skin 70 x 25 x 3mm. Central warty lesion 9 x 9 x 4mm with several smaller warty lesions.

Immunohistochemistry:
None.

Male 45 years

Mass in dome of bladder.



Specimen: Partial cystectomy.

Macro: Central mucoid mass predominately in the bladder wall.

Immunohistochemistry:
None.

Male 68 years

PSA 17. PIRADS 4 area on MRI scan. Prostate biopsies done.



Specimen: Prostate biopsy.

Macro: 2 needle cores, up to 16mm in length.

Immunohistochemistry:
n/a.

Male 75 years

Transperineal prostate biopsies. PSA 19.4. DRE T2. PI-RADS 5 Right Posterior.



Specimen: Transperineal targeted prostate biopsy.

Macro: Specimen "Abnormal Right". A needle core of pale tissue, 18mm in length.

Immunohistochemistry:
None performed.

Male 61 years

PSA: 4.9. DRE: Benign. TRUS Volume: 36cc. MRI: T2N0.



Specimen: Transperineal template prostate biopsies.

Macro: Right mid - 2 Cores received pre-cassetted.

Immunohistochemistry:
None provided.