Male 23 years

Haematuria. Odd tumour on left side of bladder.



Specimen: Transurethral resection.

Macro: Multiple fragments from 1-8 mm.

Immunohistochemistry:
N/A.

Male 65 years

Renal tumour.



Specimen: Nephrectomy.

Macro: Radical nephrectomy specimen with 60mm tumour involving upper and mid portion of the kidney.

Immunohistochemistry:
None.

Male 61 years

New TCC located at prostatic urethra.



Specimen: Urethra polypectomy.

Macro: Multiple pieces of fibrous tissue in aggregate weighing 1g, all processed in B1.

Immunohistochemistry:
None.

Male 25 years

Left testis 1cm cystic area with mural thickening. Tumour markers normal. ?Testicular tumour ?Leydig cell tumour.



Specimen: Left Orchidectomy.

Macro: Received testis (70x40x40mm) with attached cord (90mm in length). On sectioning, there is a cystic lesion 18mm in maximum dimension with some pale nodular lining. The cyst is well demarcated from the normal looking surrounding parenchyma.

Immunohistochemistry:
Positive: MOC31, CK7, CD15, CA125, PLAP, ER, PR, WT1 Negative: CK20, Calretinin, CEA.

Male 75 years

G3 pT1. BCG. Progressed to T2.



Specimen: Cystoprostatectomy.

Macro: Received is a radical cystoprostectomy specimen. Bladder including perivesicle fat is 230 x 140 x 50mm. On slicing there is ill defined tumour and some adjacent cystic areas towards the mid right wall up to 20mm. Section from cystic area.

Immunohistochemistry:
None.

Male 61 years

Abnormal area at dome ?CIS. Could also be fistula track if looks benign/inflammatory.



Specimen: Bladder biopsies.

Macro: Three pieces of tissue ranging in size from 4 to 6 mm.

Immunohistochemistry:
NA.

Male 80 years

Scrotal mass, ultrasound suggests tumour.



Specimen: Orchidectomy.

Macro: Orchidectomy specimen including testis measuring 37 x 15 x 30mm with a mass measuring 95 x 75 x 75mm present at the lower pole of the specimen. The mass is fairly well-circumscribed and solid with a light brown and white cut surface and a central necrotic area. The mass appears to be separate from the testis and is present within soft tissue.

Immunohistochemistry:
FISH shows MDM2 amplification.

Male 24 years

No clinical information given.



Specimen: Left testis.

Macro: Testis 65 x 55 x 45 mm with a haemorrhagic well circumscribed mass which is confined to testis and measures 47 x 42 x 40 mm.

Immunohistochemistry:
CD30, Glypican 3, Oct 4 and AFP.

Male 40 years

Circumcision performed.



Specimen: Foreskin.

Macro: This is a fragment of foreskin, 50 x 20 x 20 mm with thickened epithelium over an area, 30 x 20 mm.

Immunohistochemistry:
Nil.

Female 54 years

Right upper pole renal tumour.



Specimen: Partial nephrectomy.

Macro: A partial nephrectomy specimen measuring 50x25x20mm. The surgical resection margin show has been painted green. Cut surface reveals a circumscribed yellow tan lesion approximately measuring 20x22x20mm and has an approximate clearance of 2mm from the surgical margin.

Immunohistochemistry:
Positive for CA9, vimentin, CK7, CD10, AE1/AE3, EMA and negative for P504s, RCC, CD117, TFE3, CK20.

Female 73 years

Left laproscopic nephrectomy.



Specimen: Nephrectomy.

Macro: Kidney - radical nephrectomy specimen measuring 180 mm x 80 mm x 50 mm. The kidney itself measures 100 x 50 x 40 mm. In the upper pole there is a simple cyst measuring 60 mm in maximum dimension and adjacent to this there is a mahogany brown tumour with a central scar measuring 60 x 40 x 60 mm. Tumour with possible pushing into a vessel noted and sampled in block provided and macro photograph.

Immunohistochemistry:
CK7 and CD31 provided. CD117 positive, negative for vimentin.

Female 78 years

Right renal mass. Likely RCC.



Specimen: Kidney Biopsy.

Macro: 2 cores of renal tissue.

Immunohistochemistry:
Positive for PAX8. MNF116, WT1 and CD57. Negative for CK7, CA9, racemase. Ki67 index.

Male 58 years

On active surveillance for Gleason 6 prostate carcinoma. PSA rising with high PSA density.



Specimen: Prostate core biopsy.

Macro: 2 cores up to 15mm.

Immunohistochemistry:
None.

Male 72 years

PSA11, DRE: T3 right side, MRI T3 N0, prostate vol 27.49cc.



Specimen: Transperineal template prostate biopsies.

Macro: N/A.

Immunohistochemistry:
N/A.

Male 43 years

PSA: 3.9. DRE: Not stated. TRUS Volume: Not stated. MRI: PIRADS V bilaterally.



Specimen: Prostate Needle Biopsies.

Macro: 3 cores received cassetted.

Immunohistochemistry:
Triple cocktail: p63/34betaE12/AMACR (p504s).