Male 32 years

5mm punch excision. Punch excision of ? Cyst left temple.

Macroscopic description:
Punch biopsy of skin measuring 5mm in diameter x 4mm in length.

Male 68 years

Skin biopsy. Nodule lateral right foot.

Immunohistochemistry:
CD34, CD31 and HHV8 positive.

Male 53 years

Incisional skin biopsy - back. ?Pemphigus.

Macroscopic description:
Part of a skin ellipse 10x6x5mm bearing a smooth intact blister 6x4x2mm. Direct immunofluorescence showed intercellular positivity with IgG and C3 in the epidermis. IgM and IgA negative.

Male 42 years

Skin, Excision Biopsy. Sent in as epidermoid cyst from the scalp.

Macroscopic description:
Tan cystic cut surface. No lesion seen on epidermis.

Female 41 years

Skin Excision. Nodule removed from abdomen ?what. EOS 49x30x22mm with central cream and brown nodule 22mm in diameter. Diffusely posiive with S100. Mel-A and HMB45 positive only in superficial parts of invasive tumour. AE1/AE3, Synaptophysin and Chromogranin negative.

Female 59 years

6mm punch biopsy from thigh. Extensive lichenoid eruption.

Macroscopic description:
6mm punch biopsy.

Female 51 years

Incisional biopsy - R forearm. Presented with flu-like symptoms, sore throat, developed acute symmetrical rash over face, hands and forearms.

Macroscopic description:
Ellipse of skin 10x6x5mm.

Immunofluorescence negative. CRP176, WCC 6.5 Hb133 ANA negative, Blood cultures negative.

Male 53 years

Skin Excisional Biopsy. 5year history of growing skin coloured papule. Can easily be traumatised and bleed. ?Intradermal naevus. Rule out BCC. Skin excision left calf.

Female 64 years

Left lid excision. White nodular lesion ?Sebaceous Carcinoma. Specimen received consists of a wedge of skin. The specimen measures 11mm x 17mm x 5mm in depth. The surface bears a well circumscribed white nodule measuring 11mm x 9mm x up to 3mm. Tumour cells positive for Androgen receptor and patchily for EMA while being negative for CEA.

Male 48 years

Punch biopsy right leg. Clinical Diagnosis of TEN. 48 year old with HIV+ and TEN. Started same time as Isoniazid started, approximately 7 days ago. Body surface area affected >95% - only areas that are not denuded are finger tips and soles of feet.

Macroscopic description:
Punch biopsy of skin measuring 5mm in diameter x 5mm deep. Bisected and AE in A1. Frozen section sent showed only keratinous debris.