Female 70 years

History of mastectomy and radiotherapy for breast carcinoma eight years ago, recent biopsy of scar ?recurrence. Now haemorrhagic nodule above mastectomy scar ?recurrence.

Specimen: Skin biopsy - above mastectomy scar.

Macroscopic description:
Ellipse of skin 42x18x11mm with nodular lesion 20x18mm.

Female 70 years

>30 year history of intermittent blistering, erythematous rash on buttocks associated with pain then itching.

Specimen: Punch biopsy - buttock.

Male 87 years

Large fungating skin lesion.

Specimen: Skin - chest wall.

Macroscopic description:
Ellipse of skin measuring 50x83mm bearing a fungating lesion measuring 33x36x17mm.

Immunohistochemistry:
Positive: EMA, p63 and CK14. Negative: BerEP4 and CK20.

Male 62 years

Warty pink nodule of a few years duration. ?Hypertrophic lichen planus ?Lichen simplex.

Specimen: Skin - right calf.

Macroscopic description:
A piece of skin measuring 1.5x0.4x0.5cm.

Female 18 years

Halo naevus right side of neck - bleeding.

Specimen: Ellipse of skin - right side of neck.

Macroscopic description:
Ellipse of skin 26x10x8mm with a variably pigmented nodule 7x5x2mm and a surrounding halo taking the total diameter to 11x7mm.

Male 50 years

Fleshy polypoid lesion, present >5years, getting bigger. ?Seb. wart.

Specimen: Shave biopsy posterior thigh.

Macroscopic description:
shave biopsies serially sectioned.

Female 55 years

Thickened skin lateral right breast, recent weight loss.

Specimen: Skin punch biopsy - right breast.

Macroscopic description:
4mm punch biopsy of skin.

Male 71 years

?Lymphoma nodule.

Specimen: Skin chest wall.

Macroscopic description:
Ellipse of skin 45x25mm with subcutaneous tissue 15mm depth. There is a raised tan brown lesion measuring 18x10mm.

Immunohistochemistry:
Positive: CD20, CD79a, BCl2, CD10 and CD21. Negative: CD3 and CD5.

Female 73 years

Swelling on right ring finger. ?RA nodule ?Cyst.

Specimen: Excisional biopsy - right ring finger.

Macroscopic description:
Irregular piece of fibrous tissue 16x16x6mm.

Other investigation results:
Rheumatoid factor: 112 IU/ml [0-40].

Female 18 years

Multiple nodules on the scalp. This was excised by the GP ?fibroepithelial polyp.

Specimen: Scalp nodule.

Macroscopic description:
An ellipse of skin measuring 25x15mm bearing a nodule measuring 20x18x8mm.

Female 60 years

No clinical details provided.

Specimen: Biopsy from the vulva.

Female 53 years

No clinical details provided.

Specimen: Biopsy from the vulva.

Female 52 years

Asymptomatic nodules on the prepuce that have developed in the course of severall months. Thickened skin with lichenification and white discolouration.

Specimen: Biopsy from the vulva.

Female 64 years

No clinical details provided.

Specimen: Biopsy from the vulva.

Female 71 years

Nodules with erosions on the vulva. Rule out malignancy.

Specimen: Biopsy from the vulva.

Female 55 years

Crohn's disease.

Specimen: Biopsy from the vulva.