Female 48 years

?allergic contact dermatitis ?herpes.

Specimen: Biopsy left shoulder.

Macroscopic description:
Skin shave 0.6x0.3cm.

Male 46 years

Cystic lesion left upper arm.

Macroscopic description:
A punch biopsy measuring 5x3x4mm.

Immunohistochemistry:
S100 positive diffuse. Periphery EMA positive. CK5/6, melan A, HMB45, CD68 and SMA negative.

Female 78 years

Naevus dorsum left foot. Skin excision.

Macroscopic description:
Disc of skin 9x8x2mm with surface slightly warty and pigmented.

Male 44 years

Firm lumps lower legs. Previous thyrotoxicosis.

Specimen: Incisional biopsy of leg.

Macroscopic description:
Ellipse of skin with a smooth white surface.

Female 44 years

Deep seated infection in right femur. On IV antibiotics for 7-10days. 2day history of an extensive confluent erythematous rash on face and flexure with pustulation and blistering. ? SJS/TEM/AGEP.

Specimen: Incisional biopsy from chest.

Macroscopic description:
An ellipse of skin 10x4mm with subcutaneous tissue to a depth of 5mm.

Female 24 years

Changing mole on back.

Specimen: Skin.

Macroscopic description:
Skin 24 x 13 x 10mm bearing a 11 x 8mm tan and brown multinodular plaque.

Female 46 years

?metastatic squamous carcinoma left elbow. Patient had a right BKA for squamous carcinoma followed by stump metastasis, hind quarter amputation and radiotherapy. An area of ulceration within the amputation stump biopsied five months ago when no tumour was found, although subsequent bone biopsy did show infiltration by moderately differentiated squamous carcinoma.

Specimen: Not specified.

Macroscopic description:
Pale fragments together 10x10mm.

Male 47 years

Lesion right cheek.

Specimen: Excision.

Macroscopic description:
Skin ellipse bearing nodule 5mm diameter.

Female 50 years

Hard subcutaneous nodule, overlying skin with peau d'orange appearance ?sarcoma ?cutaneous metastasis ?panniculitis.

Specimen: Wide local excision.

Macroscopic description:
Ellipse of skin 130x60x35mm, poorly circumscribed pale solid yellow/white mass 22x20x15mm.

Immunohistochemistry:
S100 & PAS positive.

Female 79 years

Firm erythematous subcutaneous lesion on lower back. Previous DLE, limited cutaneous systematic sclerosis, HTLV 1 + 2.

Specimen: Incision ellipse edge of lesion.

Macroscopic description:
Skin ellipse with underlying subcutaneous tissue measuring14x8x6mm the surface is unremarkable. Specimen is longitudinally bisected.

Immunohistochemistry:
Cells are positive for CD3, CD5 and CD25, a large proportion show CD4 positivity. They are negative for CD7, CD20, CD79a, ALK-1 and CD30. The MIB-1 index is high.

Male 77 years

?BCC on forehead.

Female 63 years

Skin lesion in the left axilla present for several years.

Female 70 years

Scalp tumour.

Female 41 years

Cystic neck lesion under the sternocleidomastoid. H/o of multiple scalp tumours.

Female 72 years

Tumour on the left temporal scalp.

Male 78 years

?BCC ?adnexal tumour on the right cheek.