Female 32 years

History of common variable immunodeficiency, diagnosed 8 years earlier, presented with jaundice and was found to have cholangiopathy on MRCP and sclerosing cholangitis on biopsy.
She was transplanted (446881 and 446882). Post transplantation, bilirubin normalised, but GGT and alk phos remained elevated.

Liver biopsy (446883) is taken at 12 weeks post OLT. She developed progressive jaundice. Biopsy (446884) is taken at 5 months post OLT. Cholangiopathy was demonstrated on MRCP. She died from pulmonary sepsis 10 months post OLT.

Female 66 years

Split OLT 2008 - ALD cirrhosis. Previous early rejection. Worsening ALP/GGT March 2018. MRCP suspected iron overload. ? rejection.

Male 20 years

Liver transplant for PSC (explant, 446891). Day 3 - required stent for hepatic artery stenosis. Spiked temperature on day 5. ALT increased day 7 - TJB (446892). Discharged on day 13.

Presented with jaundice 21 months later. USS - no abmormalities.

Liver biopsy (446893). Then CT angiogram and MRCP. Listed for re-transplantation.

Liver transplant 2 years after first transplant. (446894, 446895, 446898, 446901, 446904).

Male 64 years

Liver transplant June 2019 for NAFLD and HCCx2. Acute rise in ALT >5000, imaging ? outflow obstruction. Venography - hepatic veins patent. TJB day 8 post transplant (446906).

Male 69 years

Transplanted for NASH and HCC. Re-transplanted 5 months later for clinical diagnosis of ischaemic type biliary lesions. Sections from right (446936) and left (446937) lobes of failed allograft.

Male 52 years

Transplanted in September 2011 for HCV (genotype 1a, treatment naive) and ALD cirrhosis decompensation. recurrent HCV, treated and SVR achieved in 2016. Follow-up unremarkable until earlier this year when his routine LFTs came back with ALP 210 IU/L, GGT 676 IU/L and ALT 267 IU/L. A liver biopsy was performed. His last biopsy (2015) had features of chronic hepatitis, mild, and focal portal fibrosis ?rejection.