Male 54 years

Seven months and one week later following treatment for rejection. Deranged LFTs. Has been treated for rejection. ?improved, worsened ?other pathology.

Male 54 years

Kidney/Ltx Oct 2009. Four day history of jaundice/pale stools/dark urine. ALT 1070, ALP 473, Bili 84, creat 156. USS-NAD, no duct dilatation seen. On sirolimus approximately two months. Level on admission 1.9 (low) ?cause, ?rejection

Female 50 years

OLT Feb 2010 for HCV cirrhosis. Also HIV. Persistent cholestasis beginning two months after OLT. This biopsy is four months after OLT.

Female 56 years

June 2009 OLT for HCV cirrhosis (this biopsy is one year later). Post OLT biliary anastomotic stricture. Stented and stent removed Dec 2009. Now worsening ALP & GGT. MRCP and CT show no duct dilatation.

Male 41 years

OLT April 2010 for alcoholic liver disease and haemochromatosis. Hepatic artery thrombosis post transplant.

Female 64 years

Eleven months post OLTx for hepatitis C. Previously moderate acute cellular injection seventeen days post transplant. Recurrent Hepatitis C post transplant, modified HAI stage 2, grade 7 diagnosed seven months post transplant. This biopsy eleven months post transplant. Hospital admission with tiredness, abnormal LFT's with bilirubin 130, ALK phos 1184, ALT 103, PT10, platelets 313.

Female 81 years

Previous OLT for primary biliary cirrhosis in 1993. Been on Cyclosporin with no known complications. Developed jaundice two weeks prior to biopsy. Bilirubin 300, ALT 580, ALP 332, Gamma GT 56, no signs of sepsis. Ultrasound abdomen - no focal lesions or duct dilatation. Normal LFTs seven months prior to the biopsy for fracture neck of femur at a different hospital.

Male 65 years

Liver transplant for PSC. Recent onset of Jaundice and abnormal LFT's ?rejection. Post transplant problems with biliary stricture and recurrent biliary sepsis. Recent MRI scan showed liver abscesses. Treated with antibiotics. Also has renal failure secondary to immunosuppression. Latest biopsy May 2007 showed NRH. LFT's at time of circulated biopsy (7th September 2010): AST 300, Bilirubin 470, ALP 1794. Latest immunology (May 2010) - autoantibodies negative, IgG normal.

Male 60 years

Liver transplant for alcoholic liver disease three weeks ago. Worsening LFT's. Rising AST (108), Alk Phos (1518) and Bilirubin (127). Ultrasound shows normal bile ducts/vessels. Suspected rejection. Given one bolus of steroids prior to biopsy.

Female 37 years

Transplanted Feb 2006 for PSC. Biopsy 1: July 2007, ALT increased during last month to 166, bili 17, alk phos increasing for last three months, now 1483. Biopsy 2: June 2010. Pruritus and weight loss, cholestatic LFTs, No stricture on MRCP. Alk phos increased to 2760.

Male 44 years

Transplant for NASH. Big man transplanted with rather fatty graft. Poor arterial flow on Doppler at 5 hours, but OK by 24 hours. ?biliary stricture/leak day 5 - ERCP - smooth narrowing to anastomosis, no proximal dilatation or bile leak. All vessels patent.
Biopsy on day 10 - 36827.10 Raised ALP and bilirubin. ?rejection

Sex unknown age unknown

No clinical information available.