Female 50 years

Liver transplant for autoimmune hepatitis in 1995. Been taken off Cyclosporin for nephrotoxicity. Developed abnormal LFTs. Bilirubin 295, alk phos 2467, AST 150. ?Acute rejection.

Specimen: Liver tx biopsy

Macroscopic description: 3 cm core

Male 60 years

Jaundice, no focal lesions on ultrasound.

Specimen:

Core biopsy

Macroscopic description: Two cores of pale brown tissue

Female 62 years

Abnormal LFTs. Raised Ferritin. ?Haemochromatosis.

Specimen:

Core biopsy

Macroscopic description: Three cores of tissue, two measuring 12 mm and one measuring 8 mm.

Female 37 years

Previous hemihepatectomy.

Specimen: Lymph node

Macroscopic description: Coeliac lymph node measuring 6 x 3 x 4 cm

Female 46 years

?PBC positive M2 on antibody. Normal LFTs, normal IgM.

Specimen:

Liver biopsy

Macroscopic description: Two cores of tissue measuring 10 mm and 3 mm in length.

Male 58 years

6cm mass periphery in right lobe of liver, ?primary or secondary malignancy. Further information - two liver masses on CT scan - one in segment 4 suggestive of a haemangioma, the other in segment 8. Also a 5cm mass in adrenal. Review of laboratory investigations - hCG, AFP, CA19.9, CEA, PSA all normal

Specimen:

Liver biopsy

Macroscopic description: Two pieces of tissue, all embedded.

Male 51 years

ALD and alpha-1 antitrypsin deficiency. Liver removed at time of OLTx. Incidental cyst.

Specimen: Liver (incidental cyst)

Macroscopic description: Liver 1123 gm (pieces previously removed from both lobes). Micronodular surface 1.2 cms cyst on superior surface centrally

Male 66 years

Shrunken left lobe, ?malignant, cholangiocarcinoma. Left nephrectomy for renal cancer six years previously. Weight loss and abnormal LFTs. ALT 140, BR 10, ALP 294. MRCP - NAD, ERCP - failed. Biopsy - Perls - iron encrusted collagen and heavy iron deposition within bilary epithelium and hepatocytes.

Specimen:

Core biopsy

Macroscopic description: Two cores 35mm and 10mm long

Male 25 years

Two week history of cholestatic jaundice. Chronic liver screen negative. BR550. AP276. ALT76.

Specimen:

Liver biopsy

Macroscopic description: Tan biopsy 36mm long, cut into three pieces

Male 65 years

Previous Dukes' A colorectal cancer 2004. AP resection. Liver mets at the time treated by embolisation. Now recurrent liver lesions.

Specimen: Right hepatectomy

Macroscopic description: Segment of liver 20 x 10 x 10cm. Two lesions 5 x 4 x 5cm and 4 x 3 x 3cm.

Female 28 years

Abnormal LFTs, ?PBC. Autoantibody screen including AMA is negative. Alk phos 1936 iU/L, ALT 114.

Specimen:

Liver biopsy

Macroscopic description: Core of liver tissue measuring 1.2cm in size

Male 42 years

Liver transplant for alcholic cirrhosis. ?HCC in segment 2.

Specimen: Liver resection

Macroscopic description: Liver 1450gm, cirrhotic appearances with 15mm nodule in segment 2 (block 1) and three other nodules 10-15mm (block 2).