Male 55 years

Mass found on ultrasound scan in his liver. Clinical diagnosis fibro lamellar carcinoma or HCC. Investigations: Alpha F P negative, MIB1 less than 0.5%. CK7 shows bile ductular reaction positivity within fibrovascular zones. Reticulin stain : normal pattern.

Specimen: Hepatic resection.

Macroscopic description: At macroscopy: hepatic resection showing a single mass measuring 6.5 x 5.5 x 5cm. The mass is well circumscribed with smooth cut surface. There is no evidence of necrosis or haemorrhage. The surrounding liver tissue was not cirrhotic or fibrotic.

Male 65 years

Abnormal liver function tests / Increased Mean corpuscular volume, raised ferritin.

Macroscopic description: Single liver core

Female 4 days

4 day old female. Nodule stuck to side of diaphragm

Specimen: Nodule edge of diaphragm

Macroscopic description: Crescent shaped piece of tan tissue measuring 2.3 x 0.8 x 0.8 cms

Female 53 years

Liver mets and lung lesion

Specimen:

Liver biopsy

Macroscopic description: a tan core of tissue 2cm long.

Female 43 years

?Primary biliary cirrhosis (PBC), Investigations: Bili 54, alkaline phosphatase 344, alanine transaminase 183, gamma globulin 36(+) Antimitochondrial Ab positive 1/100.

Specimen:

Liver biopsy

Macroscopic description: Two cores 12 & 13 mm

Female 24 years

Hepatitis B infective to assess degree of liver damage

Specimen:

Liver biopsy

Macroscopic description: Core of tan tissue measuring 19 mm long

Female 29 years

Abdominal pain investigation. Liver tumour found clinically/imaging. Clinically thought to be an adenoma. Resection carried out.

Specimen: Right partial hepatectomy

Macroscopic description: 20 x 15 x 10 cm liver resection specimen. Subcapsular well circumscribed nodule. Brownish in colour 4.5 x 3.5 x 3 cms diameter

Female 55 years

Abnormal liver functions: gamma glutamyl transferase 400, alanine transaminase 25, alkaline phosphatase 167, Bili 27, hepatomegaly, ?chronic. No serological clue as to cause... Ultrasound: heterogenous appearance but no obvious mass

Specimen: Trucut biopsy

Macroscopic description: Core of tan tissue 1.3 cms

Female 65 years

No other clinical details supplied with specimen No special stains undertaken

Specimen: Liver resection

Macroscopic description: 164 gm wedge of liver with a haemorrhagic lesion visible on slicing

Male 61 years

Hepatitis B positive, Hepatitis C negative, IgG normal. Antibodies negative. No drugs. alanine transaminase 90-120.

Specimen: Liver core

Male 44 years

Jaundice, ascites, abnormal clotting. Suspected Alcoholic liver disease, ?alcoholic hepatitis, ?cirrhosis

Specimen:

Liver biopsy

Macroscopic description: 20 mm core

Male 54 years

Right hepatectomy for ??? Metastases.

Specimen: Right hepatectomy

Macroscopic description: Two nodules (6.5 and 5 cm in maximum diameter). The larger nodule is greyish and the smaller nodule black