Male 28 years

Imaging features suggestive of PSC, ? autoimmune overlap ?IgG4.

Specimen:

Liver biopsy.

Macroscopic description:
1 tan core measuring 26mm, bisected.

Male 37 years

HBV. ? Fibrosis related to HBV or NAFLD. Abnormal LFTs. 18G cores.

Specimen: Needle core biopsy.

Macroscopic description:
2 cores of tissue.

Female 45 years

Acute liver failure . Liver, 1267g . Diffusely nutmeg in appearance.

Specimen: Section from expanted liver.

Macroscopic description:
Liver, 1267g . Diffusely nutmeg in appearance.

Male 68 years

Lung Adeno on Pembro. ALT62 ,ALP 675, Bili 125.

Specimen: liver biopsy.

Macroscopic description:
2 cores of liver.

Female 71 years

Newly deranged LFTs ALT 127, MRCP shows cirrhosis, non invasive screen negative (but SMA pos on system!).

Specimen: liver biopsy.

Macroscopic description:
3 cores of liver.

Male 36 years

Hepatocellular lesion on biopsy and MRI ? HCC or adenoma.

Specimen: liver.

Macroscopic description:
Liver segment 109g, 105x55x47mm. On slicing there is an ill-defined greyish irregular lesion 20mm diameter, 10mm from the nearest margin.

Female 34 years

Previous bariatric surgery/gastric sleeve. Recent bowel obstruction: Dx volvulus - Jaundiced since this. CT - Adhesional small bowel obstruction. Underwent laparotomy, small bowel resection and double-barrelled ileostomy formation. Difficult post-operative recovery complicated by poor oral intake, a midline wound infection, multiple pressure sores and jaundice of unknown aetiology. Had blood transfusion post operatively. Wound dehissed and worsening jaundice. Raised ALT >1000, raised ALP 176, raised bilirubin 82. Non-invasive liver screen was negative. CT TAP showed evidence of Endometritis for which patient is getting IV clindamycin. Liver functions remained static despite treating the sepsis ?drug induced ?NAFLD/rapid weight loss.

Specimen: Liver core biopsy.

Macroscopic description:
Single core of brown tissue measuring 25mm in length.

Male 66 years

Medisatinal adenopathy and hepatomegaly , ? lymphoma.

Specimen: liver biopsy.

Macroscopic description:
2 cores, each 20mm.

Female 19 years

Super urgent liver transplant for acute on chronic liver failure.

Specimen: explant.

Macroscopic description:
Liver 1324g, bile stained with multiple nodules up to 8mm.

Female 37 years

Budd Chiari? Trans jugular biopsy, thin core 16mm.

Specimen: biopsy.

Macroscopic description:
Trans jugular biopsy, thin core 16mm.

Male 53 years

Metastatic HCC for tissue diagnosis.

Specimen: targetted liver biopsy.

Macroscopic description:
1 core 15mm long.

Male 74 years

18 years previously diagnosed with haemochromatosis and early cirrhosis. Previous lesions treated with RFA (2010) and resection (2014). This is a new lesion in segment 3.

Specimen: Liver.

Macroscopic description:
Subcapsular wedge, 5g, 30x20x15mm. Contains a tumour 20mm max, occupying almost all of the specimen. Solid, nodular appearance, some bile stained areas. Slide 524629 - A1. Slide 524630 - A2.

Female 9 years

As given on request form 'Known AI liver disease and coeliac disease. ?non compliant'.

Specimen: biopsy educational.

Macroscopic description:
3 cores 8,8, and 10mm.