Female 65 years

NAFLD. Normal immunoglobulins and weakly positive SMA. Recent rise in LFT's. Alcohol 15 units per week.

Specimen:

Liver biopsy.

Macroscopic description:
Two cores 20mm and 17 mm.

Additional stains: Retic, Sirius red.

Male 74 years

Highish ferritin and cirrhosis, no cause found, genotype neg for haemochromatosis but if has xs iron I would venesect. Rest of liver screen neg apart from sl high IgG, ANA neg. Is there significant iron overload and any other cause of cirrhosis. Very little alcohol.

Specimen: Liver, core biopsy.

Macroscopic description:
A cylinder of tan tissue measuring 24mm plus fragments of similar tissue.

Additional stains: Sirius Red Fast Green, Perls, DPAS, A1AT.

Male 53 years

Laparoscopic cholecystectomy for gallstones-liver lesion segment 4.

Specimen: Liver resection.

Macroscopic description:
Wedge of liver 12 x 9 x 2 mm.

Additional stains: None.

Male 67 years

HCV and history of heavy alcohol. Fibroscan reassuring but low platelets. ? significant fibrosis.

Specimen:

Liver biopsy.

Macroscopic description:
2 cores 12 and 24mm long.

Additional stains: EPSR.

Male 66 years

CWT patient. Segment VIII liver lesion biopsy. + background liver biopsy (segment IV). MWA post biopsy. ?HCC.

Specimen:

Liver biopsy, segment VIII, USG 18G.

Macroscopic description:
A core of cream and tan tissue measuring 15mm in length and 1mm in diameter together with fragments measuring 3mm in aggregate.

Additional stains: None submitted to EQA.

Male 70 years

Cirrhosis.

Specimen: Liver explant.

Macroscopic description:
A total hepatectomy, weighing 2030 grams. On slicing, within segment VI and VII, there is a variegated cream/haemorrhagic/bile stained tumour with thickened capsule, which measures 40 x 29 x 22mm. The background liver shows some ill-defined nodularity.

Additional stains: None submitted for EQA.

Male 61 years

Jaundice and progressively cholestatic LFT. Dilated cardiomyopathy and liver congestion. Has ICD/CRT-D. Bili 80, ALT 12, ALP 203, GGT 312. ?Drug induced cholestasis. ?Cardiac cirrhosis. DH Rivaroxaban.

Specimen:

Liver biopsy, USG plugged.

Macroscopic description:
Three tan cores measuring 5, 7 and 17mm.

Additional stains: None submitted to EQA.

Male 55 years

Sepsis of unknown origin. Fever, night sweats, rigor and lethargy. Intravesicle injection BCG for bladder cancer 2 months previously. Deranged liver function tests.

Specimen: Liver Biopsy.

Macroscopic description:
15mm strand of tissue.

Additional stains: NONE.

Female 62 years

Obstructive jaundice secondary to biliary adenoma [sic].

Specimen: Native liver, hepatectomy.

Macroscopic description:
Intraductal lesion within CBD, CHD and into R/LHD.

Additional stains: Nil.

Female 69 years

High suggestion of fibrosis. Benign biliary stricture ? secondary to chronic pancreatitis.

Specimen:

Liver biopsy.

Macroscopic description:
Tan core 25mm.

Additional stains: HVG.

Male 66 years

Cardiac cirrhosis? under investigations. Mild constrictuive pericarditis/bicuspid aortic valve with tissue valve replacement. Any evidence of cirrhosis? drug induced liver injury? alcohol related?

Specimen: Transjugular liver biopsy.

Macroscopic description:


Liver biopsy - three cores 15mm max.

Additional stains: EVG, CK7.

Female 50 years

Hepatic adenoma 100K Genome project sent fresh. Not sampled for Genome project.

Specimen: Left lateral sectionectomy (segments 2 and 3).

Macroscopic description:
Specimen weight: 411g. Specimen dimensions: Supero-inferior180mm, Medio-lateral 105mm, Antero-posterior 45mm Tumour appearance: Multinodular, irregularly shaped, tan with interspersed vessels, and focal central ?fibrosis., Tumour size: 115mm x 95mm x 45mm.

Additional stains: Keratin 7, Glutamine synthetase, van Gieson, Shikata.