Female 56 years

PBC. Staging. This is 2/3 of the specimen the other 1/3 for research.

Specimen:

Liver biopsy.

Macroscopic description:
Single tan core 18mm.

Immunohistochemistry:
Nil.

Additional stains:

van Gieson, Rhodanine.

Male 47 years

Elevated Fibroscan. ? Cirrhosis.

Specimen:

Liver biopsy.

Macroscopic description:
1 core 15mm.

Immunohistochemistry:
NA.

Additional stains:

Masson Trichrome.

Female 91 years

Likely HCC on imaging in segment 6 with small satellite lesions, non-cirrhotic.

Specimen: Liver segement 5/6.

Macroscopic description:
140x110x40mm liver segment. slicing shows a 65x50x50mm tumour with a variegated appearance including areas of necrosis and haemorrhage. it is 28mm from the resection margin. three smaller satellite nodules. section from main lesion.

Immunohistochemistry:
Hepar R1 synaptophysin, melan A and S100.

Female 72 years

Acute hepatitis, cause? seronegative autoimmune hepatitis?

Specimen:

Liver biopsy.

Macroscopic description:
Tan core 19mm.

Immunohistochemistry:
None.

Additional stains:

van Gieson.

Male 20 years

Heptatitic picture, autoimmune, AIH? IgG 19.67g/l, ANA+ (1:100) f actin+ and SMA+. AMA-. Bili 73, ALT 946 ALP 256.

Specimen:

Liver biopsy.

Macroscopic description:
2 tan cores 13mm and 3mm.

Immunohistochemistry:
None.

Additional stains:

Reticulin, Shikata, van Gieson.

Male 73 years

Liver resection for HCC. Additional nodule visualised on liver.

Specimen: Subcapular liver resection.

Macroscopic description:
4mm fragment of liver.

Immunohistochemistry:
None.

Female 69 years

Deranged LFT's AST/ALT>800. IgG increased, ?autoimmune hepatitis.

Specimen:

Liver biopsy.

Macroscopic description:
16mm core.

Immunohistochemistry:
None.

Additional stains:

Reticulin, Sirius Red.

Male 26 years

Cryptogenic liver cirrhosis. Chronic Budd Chiari?

Specimen: Transjugular liver biopsy.

Macroscopic description:
Tan core 18mm.

Immunohistochemistry:
Nil.

Female 29 years

Hydatid cyst resection.

Specimen: Segment V liver.

Macroscopic description:
Segment of liver 85 x 70 x 70 mm with a cyst 68 x 50 x 30 mm.

Immunohistochemistry:
None.

Female 57 years

Fatty liver, previous positive antibodies and raised IgG. significantly elevated fibroscan suggestive of cirrhosis - liver biopsy to assess/stage disease.

Specimen:

Liver biopsy.

Macroscopic description:
One core 23mm long.

Immunohistochemistry:
None.

Additional stains:

van Gieson, Retic, Shikata, Cam 5.2.

Female 75 years

Abnormal LFTs and jaundice.

Specimen:

Liver biopsy.

Macroscopic description:


Liver biopsy core 21 mm long.

Immunohistochemistry:
None.

Additional stains:

van Gieson, Retic, PASD, Shikata.

Male 67 years

History of primary carcinoid lung tumour with solitary liver metastasis. Metastasectomy performed.

Specimen: Liver segment 4b.

Macroscopic description:
Liver disc 7.8cm diameter x 3.3cm deep. Nodule measuring 2.2cm, 0.6cm from the deep margin.

Immunohistochemistry:
Chromogranin, PSA, CK20, CK7, TTF, S100, Synapto.