Female 60 years

ALT 1102; Gamma GT 84; Raised IgG. Alk phosphatase normal. ANA positive 1:80; Anti Smooth muscle AB positive. AMA negative. IgM normal. History breast carcinoma.

Specimen: Liver Biopsy.

Macroscopic description:
2 cores of liver combined length 25mm.

Immunohistochemistry:
Reticulin, PAS, Masson.

Female 63 years

Chronic pancreatic insufficiency. Type 2 diabetic on insulin, Deranged LFTs, fatty liver on ultrasound, elevated fibroscan.

Specimen:

Liver biopsy.

Macroscopic description:
Two cores of liver 18mm and 17mm.

Immunohistochemistry:
Picro Sirius red, reticulin.

Male 53 years

History of alcohol excess, currently abdominal pain, jaundice. Liver screen normal, ?fatty liver on CT, oesophageal varices.

Specimen:

Liver biopsy.

Macroscopic description:
Two cores 20mm and 17mm.

Immunohistochemistry:
Picro Sirius red, reticulin.

Male 4 years

Abnormal LFTs, AMA strong +ve, fatty liver on ultrasound, ?PBC.

Specimen:

Liver biopsy.

Macroscopic description:
One core 20mm.

Immunohistochemistry:
Picro Sirius red, reticulin, the Orcein was negative for copper associated protein.

Male 74 years

'Liver lesion segment 6/7'. From electronic patient record IgG kappa paraproteinaemia. Section is from background liver.

Specimen: Non anatomical resection segment 6/7.

Macroscopic description:
292g liver wedge containing a 9cm tumour. The section submitted is from background liver not the tumour.

Immunohistochemistry:
PASD, Masson trichrome, IgG, lamda, kappa, congo red.

Male 85 years

Recurrent abscess in left lobe of liver.

Specimen: Partial liver resection.

Macroscopic description:
Left lobe of liver: segment of liver measuring 135 x 85 x 40mm. On slicing there is a cystically dilated area measuring 20mm. Macropath image has been taken.

Female 51 years

Chronic hepatitis C. Positive mitochondrial antibodies and raised IgG. Type II diabetes and obesity.

Liver biopsy to rule out autoimmune hepatitis.

Specimen:

Liver biopsy.

Macroscopic description:
One core, 20mm long.

Immunohistochemistry:
VG, CK8/18.

Male 69 years

? HCC pre-ablation. 18G biopsy.

Specimen:

Liver biopsy segment VI.

Macroscopic description:
One core, 12mm long plus fragment.

Immunohistochemistry:
Perls (little tissue left in block).

Female 49 years

Acute Hepatitis.

Liver biopsy. Additional information from urgent

Liver biopsy booking from 'BG hypothyroidism. A/W Deranged LFT's. Acute hepatitis, Coagulopathy, high IgG hepatitis negative, ? Autoimmune hepatitis'.

Specimen:

Liver biopsy.

Macroscopic description:
One green speckled core of Liver tissue measuring 20mm in length.

Immunohistochemistry:
VG, DPAS, Shikata.

Female 53 years

Increased fibroscan (11) ?NAFLD ?degree of fibrosis.

Specimen:

Liver biopsy.

Macroscopic description:
20mm core.

Immunohistochemistry:
Alpha 1 antitrypsin, ubiquitin, cytokeratin 8/18, PASD, HVG.

Female 43 years

Intra-abdominal mass involving right lobe of liver.

Specimen: Right hemihepatectomy.

Macroscopic description:
Segment of liver 265x175x115mm almost completely occupied by a circumscribed haemorrhagic lesion.

Female 28 years

Lesion left lobe liver.

Specimen: Left lobe liver.

Macroscopic description:
Liver resection 135x95x60mm with a circumscribed lesion 35x32x24mm.