Male 43 years

To stage fibrosis/cirrhosis. ?aetiology - AIH, PSC, other. ALT 2-3x normal, GGT and Alk phos 4-5 x normal, IGG raised, antibodies negative apart from positive anti PR3.

Specimen: Biopsy.

Macroscopic description:
Core of tissue 24mm. (ID 385)

Male 48 years

Presumed NAFLD. Type 2 diabetes. BARD = 4. Ferritin 800 (HFE Gene negative) Raised fibroscan.

Specimen:

Liver biopsy.

Macroscopic description:


Liver biopsy: a yellowish core 17mm long. (ID 391).

Female 60 years

Deranged LFTs, ALT>1100, SMA+ve.

Specimen: Biopsy.

Macroscopic description:
Single core 17mm. (ID 386).

Female 74 years

Acute hepatitis,ALT >1000, SMA+ve.

Specimen: Biopsy.

Macroscopic description:
Two cores 19mm and 18mm. (ID 387).

Female 52 years

Portal hypertension, biliary sepsis, renal transplantation 7 years earlier.

Specimen: Liver.

Macroscopic description:
Fine parenchymal nodularity. No tumour. (ID 375).

Male 60 years

Background alcohol excess. Hepatoma screening identified exophytic lesion section II/III. AFT raise-CT strongly suggestive hepatoma. Laparoscopic left lateral sectionectomy.

Specimen: Excision Liver Segments II/III.

Macroscopic description:
100g of liver 8.3x5.7x4cm. Single lobulated exophytic mass 5cm in diameter, excised by 1.2cm. (ID 377).

Female 44 years

Rheumatoid arthritis, derranged LFT's ?source, from clinic letter - patient has been taking methotrexate for 10 years at 25mg per week for 6 years then 15mg per week for four years. Normal liver function tests, presented with low platelets. Liver screen - elevated IgG, nil else.

Specimen: Liver Biopsy.

Macroscopic description:
One core 16mm. (ID 380).

Female 36 years

Chronic liver disease - maybe due to alcohol. Also has SMA +ve and EBV IGM +ve.

Specimen: Liver Biopsy.

Macroscopic description:
19mm core. (ID 383).

Male 31 years

Cardiac disease, coarse echotexture on USS, fibroscan showing fibrosis of liver.

Specimen: Liver Biopsy.

Macroscopic description:
14mm core biopsy. (ID 382).

Female 33 years

Raised IgG (27.6) and IgM (5.1) Positive AMA M2, LKM-1. persistently abnormal LFTs, USS splenomegaly ?AIH/PBC overlap.

Specimen: Liver Biopsy.

Macroscopic description:
One core 17mm long. (ID 381).

Female 24 years

Suspicious liver cyst. No history of cholecystitis.

Specimen: Liver Cyst.

Macroscopic description:
Cystic structure measuring 84x55x41 mm with a smooth external surface. It weighs 112 grams. It is a multilocular cyst with thin simple septations. No papillae identified. Cyst fluid was clear. (ID 376).

Female 43 years

Completion hepatectomy colorectal liver mets.

Specimen: Right Hepatectomy.

Macroscopic description:
Liver 17.5x12x7cm weighing 633g. On slicing there is a nodular tumour measuring 8.3x8.3x7. tumour shows evidence of focal necrosis and possible embolisation coil material wihtin some nearby vessels. Background liver appears finely nodular. (ID 374).