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EQA

Head and Neck Histopathology National EQA X - Autumn 2026







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Case 01

Female 77 years

Pigmented patch anterior gingival sulcus.

Specimen: Attached gingiva

Macroscopic description: Pigmented mucosa 5x2x2mm.


H&E 1


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Case 02

Female 40 years

Asymptomatic lesion lower right quadrant

Specimen: Cyst wall LR78

Macroscopic description: Three pieces of tissue 3 to 5mm.


H&E 10


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Case 03

Female 61 years

Multiple cystic lesions, biopsy anterior mandible.

Specimen: Mandible

Macroscopic description: Four fragments up to 6mm.


H&E 11


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Case 04

Female 16 years

Radiolucency associated with impacted left third molar tooth.

Specimen: Odontogenic

Macroscopic description: Soft tissue.


H&E 12


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Case 05

Male 58 years

Dentigerous cyst associated with unerupted & displaced upper right third molar.

Specimen: Jaw cyst

Macroscopic description: Part of a cyst wall 10 x 3 mm with a thickness of 1 mm


H&E 13


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Case 06

Male 40 years

Incidental homogeneous white patch on right lateral border of tongue. Ex-smoker of 7 years. ?Frictional keratosis

Specimen: Oral mucosal biopsy

Macroscopic description: Two pieces of mucosa, larger 5 x 3 mm to a depth of 2 mm


H&E 14


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Case 07

Female 37 years

Swelling posterior hard palate, 1 week after prolonged labour. Palatal trauma?

Specimen: Mucosa

Macroscopic description: Mucosa 6x3x3mm.


H&E 15


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Case 08

Male 69 years

Total laryngectomy yielding right-sided transglottic pT3 pN0(i+) M0 SCC. Sample is an incidental multiloculated cyst near isthmus of thyroid gland 19 x 15 x 8 mm

Specimen: Cyst in neck

Macroscopic description: Multiloculated cyst near isthmus of thyroid gland 19 x 15 x 8 mm, serous fluid released on slicing.


H&E 16


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Case 09

Female 50 years

Core biopsy parotid

Specimen: Core biopsy

Macroscopic description: 2 core biopsies


H&E 17


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Case 10

Female 45 years

Midline cyst in neck just superior to body of hyoid bone; moves on swallowing

Specimen: Cyst in neck

Macroscopic description: Intact cyst 25 x 15 x 9 mm adjacent to 19 mm segment of hyoid bone; opaque serous fluid released on slicing


H&E 18


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Case 11

Male 45 years

Infection following extraction of left lower canine tooth. Antibiotics x2. Persistent

Specimen: Left mandible, bone

Macroscopic description: Firm bone tissue 18 x 10 x 4 mm.


H&E 2


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Case 12

Male 64 years

Non healing ulcer jct of hard and soft palate

Specimen: hard soft palate

Macroscopic description: Pot contains multiple mucosal pieces measuring in aggregate 7 x 6 x 2 mm.


H&E 3


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Case 13

Female 64 years

Oral lesion, lymph node?

Specimen: Core biopsy

Macroscopic description: One core 25 mm


H&E 4


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Case 14

Female 73 years

Vallecular cyst. Right vallecula.

Specimen: Laryngeal biopsy

Macroscopic description: Polypoid soft tissue 9 x 7 x 5 mm. Bisected.


H&E 5


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Case 15

Male 40 years

Tongue base mass

Specimen: Tongue base

Macroscopic description: Ovoid tissue piece, smooth surface measuring 10 x 8 x 7 mm, serially sliced into 4 pieces, all submitted.


H&E 6


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Case 16

Female 76 years

Primary hyperparathyroidism. Enlarged nodes?

Specimen: Right neck. Lymph node or parathyroid?

Macroscopic description: soft tissue 8 x 8 x 5 mm. 0.14 g. Bisected. Immunohistochemistry: Lymphoma panel negative.


H&E 7


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Case 17

Male 54 years

Incidental thyroid tissue accompanying larynx for SCC.

Specimen: Left thyroid lobe, adjacent to total laryngectomy

Macroscopic description: Left thyroid lobe, adjacent to total laryngectomy - 93 x 50 x 30 mm.


H&E 8


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Case 18

Female 70 years

Middle ear

Specimen: Ear

Macroscopic description: Multiple fragments of tan tissue largest 5 mm.


H&E 9


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