This website uses cookies to allow us to see how the site is used. The cookies cannot identify you. If you continue to use this site we will assume that you are happy with this.
If you would like to know more, you can view our privacy statement here.

Close
EQA

Head and Neck Histopathology National EQA T - Spring 2024







How to adjust washed-out/too bright images in ImageScope (Use the back button to return here)



Case 01

Male 58 years

Left maxilla. Previous surgery.

Specimen: Maxilla.

Macroscopic description:
Firm tissue 35x34x12mm.

Immunohistochemistry:
N/A.


H&E 1


Open Slide with:
Website | ImageScope

Case 02

Male 49 years

White patch dorsum of tongue. Appeared 6 months ago. Homogeneous. Papular / reticular appearance.

Specimen: Mucosa.

Macroscopic description:
11x5x2mm piece of tissue.

Immunohistochemistry:
N/A.


H&E 2


Open Slide with:
Website | ImageScope

Case 03

Male 53 years

Cyst left maxilla. Biopsy from gingival crest.

Specimen: Gingivae.

Macroscopic description:
Smooth mucosa 9x4x3mm. Bisected.

Immunohistochemistry:
N/A.


H&E 3


Open Slide with:
Website | ImageScope

Case 04

Male 12 years

Gingival overgrowth localised to LR21 causing spacing between teeth. Bone levels normal. 10 months duration.

Specimen: Gingivae.

Macroscopic description:
Sessile nodule with ulcerated mucosa 17x16x4mm.

Immunohistochemistry:
N/A.


H&E 4


Open Slide with:
Website | ImageScope

Case 05

Female 42 years

Excision right mandibular lesion LR6 region. PTH normal range.

Specimen: Mandible.

Macroscopic description:
Blue grey mucosa covering dark brown tissue.

Immunohistochemistry:
N/A.


H&E 5


Open Slide with:
Website | ImageScope

Case 06

Female 52 years

Previous T1N3b SCC right lateral tongue. Since surgery hyperkeratotic lump ono right tongue on flap. Hyperkeratosis/dysplasia?

Specimen: Biopsy from skin flap intraorally.

Macroscopic description:
Irregular piece of mucosa 9x6x3.

Immunohistochemistry:
None.


H&E 6


Open Slide with:
Website | ImageScope

Case 07

Male 37 years

Right parotid lesion ? Pleomorphic adenoma.

Specimen: Excisional biopsy right parotid.

Macroscopic description:
Nodule of soft tissue 10 x 9 x 7.

Immunohistochemistry:
None.


H&E 7


Open Slide with:
Website | ImageScope

Case 08

Male 66 years

Ulcers lips, sore throat and tongue. Erythema soft palate and fauces / oropharynx. Red / white patch upper lip.

Specimen: Mucosa.

Macroscopic description:
Ellipse of mucosa 7x5x3mm.

Immunohistochemistry:
N/A.


H&E 8


Open Slide with:
Website | ImageScope

Case 09

Female 80 years

1.5 x 1.5 cm pedunculated swelling lump right ear / inferior concha / skin.

Specimen: Lesion right ear stitch 12 o'clock.

Macroscopic description:
An ellipse of skin measured with underlying cartilage with marker stitch superior with a central exophytic nodule measuring 22 mm presumed medial to lateral, 12 mm superior inferior and 26 mm superficial deep. Ellipse of skin 21 x 11 mm x 6 mm deep, bearing a nodular lesion 11 mm in maximum dimension.

Immunohistochemistry:
None.


H&E 9


Open Slide with:
Website | ImageScope

Case 10

Female 3 years

Lump in neck.

Specimen: Lump right neck.

Macroscopic description:
Firm, tan coloured piece of soft tissue 70x 41x 33mm. Slicing shows a pale coloured circumscribed nodule.

Immunohistochemistry:
None.


H&E 10


Open Slide with:
Website | ImageScope

Case 11

Female 68 years

Indurated lesion dorsum of tongue invading base. Looks clinically ? - 4 cm wide. Very suspicious of squamous cell carcinoma.

Specimen: Biopsy tongue.

Macroscopic description:
Irregular piece of pale mucosa 22 x 9 x 6 mm. Bisected longitudinally all embedded.

Immunohistochemistry:
Diffuse strong expression of CK 7 and EMA. There is focal luminal expression of CEA and widespread abluminal expression of p40 and p63. There is no significant expression of CK20, calponin, SMA, S100, CD117, oestrogen receptor, CDX 2 or TTF-1.


H&E 11


Open Slide with:
Website | ImageScope

Case 12

Male 67 years

Recurrent pain/ discomfort right submandibular gland.

Specimen: Right submandibular gland.

Macroscopic description:
Submandibular gland measuring 38 x 22 x18mm. Slicing reveals a yellow coloured hard tissue fragment.

Immunohistochemistry:
N/A.


H&E 12


Open Slide with:
Website | ImageScope

Case 13

Male 27 years

Tonsil with attached cystic lesion.

Specimen: Right tonsil.

Macroscopic description:
Multiple irregular fragments of soft tissue together 39 x 25 x 14mm and weighing 5.1g.

Immunohistochemistry:
N/A.


H&E 13


Open Slide with:
Website | ImageScope

Case 14

Female 40 years

Mass right orbit.

Specimen: Lacrimal gland.

Macroscopic description:
Nodule 35x35x20mm with a grey / white cut surface.

Immunohistochemistry:
N/A.


H&E 14


Open Slide with:
Website | ImageScope

Case 15

Male 30 years

Tumour right carotid bifurcation.

Specimen: Right neck lump.

Macroscopic description:
Nodule of brown coloured soft tissue 34 x 25 x 15mm. Cut surface reveals a tan coloured cut surface.

Immunohistochemistry:
CD56, synaptophysin, chromogranin positive. Some cell groups with a peripheral rim of S100 positive cells.


H&E 15


Open Slide with:
Website | ImageScope

Case 16

Male 44 years

Large soft non-fluctuant non-painful mass posterior/ nape of neck. Overlying skin normal; no lymphadenopathy.

Specimen: Soft tissue biopsy.

Macroscopic description:
Soft tissue mass measuring 100 x 100 x 25 mm, weighing 231 g. Uniform fatty appearance on slicing.

Immunohistochemistry:
None.


H&E 16


Open Slide with:
Website | ImageScope

Case 17

Female 54 years

Persistent growth inside (L) nostril, present 2 -3 years. ?Papilloma.

Specimen: Nasal vestibule biopsy.

Macroscopic description:
Warty soft tissue measuring 7x6x6mm. Bisected and submitted in total.

Immunohistochemistry:
None.


H&E 17


Open Slide with:
Website | ImageScope

Case 18

Female 49 years

Hoarse voice. Vocal cord nodule.

Specimen: Larynx.

Macroscopic description:
Two pieces soft tissue each 4 mm.

Immunohistochemistry:
N/A.


H&E 18


Open Slide with:
Website | ImageScope