Female 4 years

Patient with defective enamel affecting ULABCD, ULA and B not fully erupted and ULA very angled towards the lip. ULA and B buccal sinuses, no history of trauma. This section is a decal section of 1 of the 2 submitted teeth.

Specimen: Deciduous tooth.

Macroscopic description:
Two incisor deciduous teeth 10x5x5mm and 10x6x5mm. Both have pitted enamel with faint white and brown speckles. Length of the root is in keeping with resorption. The root surfaces are slightly irregular. The slightly larger tooth has bulging enamel at the cervical portion buccally and palatally.

Immunohistochemistry:
-

Female 72 years

Widespread white patches and ulceration to buccal mucosa, gingival tissue, dorsal tongue. No relief from steroid mouthwash or tablet.

Specimen: Left buccal mucosa, incisional biopsy.

Macroscopic description:
A piece of mucosa measuring 7 x 4 mm.

Immunohistochemistry:
IgG direct immunofluorescence showed intercellular/basketweave expression.

Male 19 years

Fluctuant, translucent cystic lesion. Lower labial mucosa. D/D: Mucocele.

Specimen: Soft tissue lesion lower labial mucosa.

Macroscopic description:
An ellipse of mucosa measuring 8 x 6 mm with an underlying cystic structure 12 x 8 x 8 mm. Longitudinally bisected.

Immunohistochemistry:
N/A.

Female 30 years

Significant gingival swelling ~1.5 cm x 1.5 cm. Interprox. 44, 45. No bony pathology noted.

Specimen: Recurrence of calcifying fibrous epulis (R) mandible gingivae interprox. 44, 45 extending lingually.

Macroscopic description:
A greyish-cream nodule of mucosa measuring 18 x 8 x 10 mm. Bisected longitudinally.

Immunohistochemistry:
N/A.

Female 18 years

6-month history swelling right mandible, firm. Bony expansion right buccal sulcus. ? Odontogenic tumour / aneurysmal bone cyst.

Specimen: Incisional biopsy right mandible.

Macroscopic description:
A disrupted cystic structure received in three fragments, together measuring 35 x 25 x up to 6 mm.

Immunohistochemistry:
N/A.

Male 53 years

Radiolucent, from 46-33, multilocular, well-defined, corticated. ? Keratocyst.

Specimen: Anterior mandible, around midline.

Macroscopic description:
An irregular piece of soft tissue 35 x 10 x 5 mm. Processed whole for two levels.

Immunohistochemistry:
N/A.

Female 61 years

Previously ruptured cyst. Seb. cyst right cheek.

Specimen: Skin of right cheek, excision.

Macroscopic description:
An ellipse of skin measuring 12 x 5 mm with underlying nodule 5 mm in maximum dimension. Bisected. Both halves processed for 2 levels.

Immunohistochemistry:
N/A.

Male 58 years

Lump right parotid gland.

Specimen: Parotid gland.

Macroscopic description:
Irregular salivary gland tissue 35 x 25 x20mm. Slicing shows a tumour, 20mm maximum.

Immunohistochemistry:
N/A.

Female 67 years

Small lump associated with grossly carious tooth. DD: ? Pyogenic granuloma.

Specimen: Lesion (L) mandible.

Macroscopic description:
A wedge of mucosa measuring 12 x 9 x 3 mm. Bisected.

Immunohistochemistry:
N/A.

Male 54 years

Enlarged gingiva lingual LR34. 6 x 5 mm erythematous, smooth sessile swelling, involving interdental papilla. Fibroepithelial polyp/pyogenic granuloma?

Specimen: Gingiva.

Macroscopic description:
Piece of white tissue measuring 7 x 4 x 4 mm.

Immunohistochemistry:
S100 strong diffuse positive. CD34 and Neurofilament positive.

Female 81 years

Lump left parotid.

Specimen: Parotid gland.

Macroscopic description:
Salivary gland tissue 35 x 30 x 28mm.

Immunohistochemistry:
N/A.

Male 50 years

History of SCC left retromolar trigone/oropharynx - surgery and chemoradiotherapy 2021. Attended for debridement of osteoradionecrosis of left mandible today. ? Necrotic bone.

Specimen: Left mandible, ulcer, bone.

Macroscopic description:
Fragments of firm soft tissue ranging from 3 x 2 x 2 mm to 4 x 3 x 2 mm.

Immunohistochemistry:
None.

Female 32 years

? Cyst right supraglottis.

Specimen: Right supraglottis/aryepiglottic fold region.

Macroscopic description:
A piece of soft tissue measuring 4 x 4 x 3 mm. Bisected. Both halves processed.

Immunohistochemistry:
None.

Male 33 years

Likely benign. Thyroglossal duct cyst.

Specimen: Thyroglossal duct cyst; excisional biopsy.

Macroscopic description:
A piece of firm grey-brown soft tissue with bone at one edge. Measures 42 x 26 x 10 mm. Soft tissue separated and serially sliced. Bone to decal. All processed.

Immunohistochemistry:
None.

Female 57 years

Right nasal polyp.

Specimen: Right nasal polyp.

Macroscopic description:
Multiple irregular and partly polypoid fragments of opalescent and haemorrhagic mucosa in aggregate measuring 60 x 45 x 10 mm. Larger pieces are serially sliced. All processed.

Immunohistochemistry:
None.

Male 47 years

Left external auditory canal. Lump.

Specimen: Left external ear canal, lump.

Macroscopic description:
Nodule of pale grey soft tissue measuring 5 x 3 x 3 mm. Bisected. Both halves processed.

Immunohistochemistry:
None.

Female 56 years

Heavy smoker and drinker. Clinical right Reinke's oedema.

Specimen: Right vocal cord.

Macroscopic description:
A piece of pale gelatinous mucosa measuring 11 x 7 x 4 mm. Bisected. Both halves processed.

Immunohistochemistry:
None.

Female 32 years

? Branchial cleft cyst in 2020, aspirated to dryness, not recurred in 2 years. ? Cyst.

Specimen: Left level II, subcutaneous tissue.

Macroscopic description:
A piece of soft tissue measuring 41 x 10 x 8 mm. Surface inked blue. Serially sliced. The cut surfaces show areas of fibrosis, yellowish-cream soft tissue, and haemorrhage. All processed.

Immunohistochemistry:
None.