Male 39 years

Raised keratotic well defined lesion lingual torus LL45 region. 3mm diameter. Present 7 years. Smoker. Case type Oral.

Specimen: Gingivae.

Macroscopic description:
Mucosa 12 x 8 x 3 mm.

Immunohistochemistry:
None.

Female 40 years

Firm nodule dorsum of tongue. Present for months. Case type Oral.

Specimen: Tongue.

Macroscopic description:
Mucosa 15 x 12 mm with firm tissue to depth of 9 mm.

Immunohistochemistry:
None.

Female 24 years

Circumscribed multilocular cyst extending from LR3 to LR6. Impacted LR3. Case type Oral.

Specimen: Odontogenic.

Macroscopic description:
Cystic soft tissue 30 x 24 x 18 mm.

Immunohistochemistry:
None.

Male 89 years

Thickened mucosa, dorsum of tongue close to midline. Case type Oral.

Specimen: Oral mucosa.

Macroscopic description:
-

Immunohistochemistry:
-

Male 49 years

Cystic lesion floor of mouth. Case type Oral.

Specimen: Oral mucosa.

Macroscopic description:
-

Immunohistochemistry:
-

Male 47 years

White patch present for one year left buccal mucosa at commissure. Central red area with 'sun ray' white patch around it, area soft. ? Traumatic, ? dysplastic. Case type Oral.

Specimen: Incisional biopsy left buccal mucosa.

Macroscopic description:
Mucosal ellipse of 10 x 8 x 2 mm, ae.

Immunohistochemistry:
NA.

Female 37 years

No clinical information provided. Three specimens submitted all with similar histology. Case type Combined.

Specimen: Skin.

Macroscopic description:
Skin with central pale nodule 10 x 8 x 7 mm.

Immunohistochemistry:
-

Male 59 years

2.5 cm parotid mass. Present months. Smoker. Case type Combined.

Specimen: Parotid.

Macroscopic description:
Superficial parotidectomy with thinly encapsulated cystic tumour 34 x 17 x 10 mm.

Immunohistochemistry:
None.

Male 65 years

Dark area 3 mm diameter overlying mucosa of alveolar ridge LLQ. Case type Oral.

Specimen: Soft tissue lesion lower left quarter alveolar ridge mucosa.

Macroscopic description:
3 mm piece of mucosa.

Immunohistochemistry:
NA.

Male 61 years

Macroglossia ? Fatty infiltration. Present for years. Affecting left and right tongue. Case type Combined.

Specimen: Tongue.

Macroscopic description:
Lateral border of tongue 74 x 38 x 20 mm. Cut sections reveal nodules of fat throughout muscle and extending to surgical margins. Focal haemorrage, no necrosis.

Immunohistochemistry:
Karyotype FISH analysis shows no evidence of MDM2 amplification.

Female 86 years

Excision lesion palate 7x6x5mm. Case type Oral.

Specimen: oral - salivary.

Macroscopic description:
-.

Immunohistochemistry:
Positive: MNF116, CK7, p63, CK5, 34BE12, EMA. Focal positivity with CEA. Negative: S100, TTF1, CK20, CD10, PAX-8, vimentin, SMM, SMA and calponin. MIB 1 - low.

Female 56 years

Slow growing lesion left neck from dorsal root C3. ? Nerve. Left posterior triangle. Present 20 years. Case type Combined.

Specimen: Neck.

Macroscopic description:
Five bosselated nodules of soft tissue collectively measuring 55 x 45 x 15 mm.

Immunohistochemistry:
S100 positive.

Female 55 years

Recurrent neck swelling. Case type Combined.

Specimen: Neck lump.

Macroscopic description:
-

Immunohistochemistry:
-

Male 35 years

Large retropharyngeal mass. Case type ENT.

Specimen: Retropharyngeal mass.

Macroscopic description:
Well circumscribed lesion measuring 92 x 55 x 50 mm. On sectioning the lesion appears multicystic.

Immunohistochemistry:
None.

Female 18 years

Painful left neck lump excised. Case type Combined.

Specimen: neck lump.

Macroscopic description:
-

Immunohistochemistry:
-

Male 80 years

Right superficial parotidectomy. Case type ENT.

Specimen: Parotid.

Macroscopic description:
Parotid tissue 67 x 44 x 30 mm with a circumscribed mass replacing the majority of the specimen.

Immunohistochemistry:
None.

Male 36 years

Lesion left nostril. Case type ENT.

Specimen: nasal.

Macroscopic description:
-

Immunohistochemistry:
-

Female 84 years

Right side thyroid mass, 22mm in diameter. Case type ENT.

Specimen: Thyroid.

Macroscopic description:
Not provided.

Immunohistochemistry:
-