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EQA

Endocrine EQA circulation 46





Case 1

Female 17 years

Right U3/4 Thyroid Neoplasm.

H&E 594392


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Case 2

Female 37 years

Rapidly growing Left Thyroid Lobe mass, >6cm, U5, Thy 5, PET scan - no other sites of PET avid disease, mild uptake in left level 4 and right level 4 lymph nodes.

H&E 594397


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Case 3



Middle aged female. Left hemithyroidectomy Thy3a aspirate.

H&E 594401


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Case 4



Young female, right ovarian dermoid cyst removed at caesarean section, section from dermoid cyst.

H&E 594406


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H&E 594410


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Case 5



Middle aged female, right hemithyroidectomy for U2 nodule.

H&E 594435


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H&E 594440


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PAX8 594414


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TTF1 Thyroid transcription factor 594421


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Thyroglobulin 594428


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Panck 594445


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P53 594451


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Case 6

Female 65 years

Incidental Lower neck lump, no compressive symptoms initially, then became symptomatic. Probable family history of goitre (grandmother). U3/4. Thy3a. Nodular thyroid intra-operatively with no concerning features.

Macroscopic description:
38x29x36mm well circumscribed but unencapsulated solid cream coloured tumour abutting capsular margins, 2mm clear of isthmic margin. Vague brown mottling suggestive of haemorrhage.

H&E 594462


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H&E 594466


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AB/PASD Alcian blue with PAS diastase 594458


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Case 7

Female 38 years

Excision of thyroglossal duct cyst. Brown cystic nodule, 35mm IME with hyoid bone attached. Mucinous material on surface, ?from cyst. On sectioning the cyst appears multiloculated and contains colloid like material.

H&E 594471


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H&E 594475


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Case 8

Female 46 years

Thyroid tumour with lymph node, bone and liver metastases. Total thyroidectomy and bilateral neck dissections.

H&E 594491


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H&E 594480


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H&E 594485


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Calcitonin 594496


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Case 9

Female age unknown

Hyperparathyroidism, left inferior parathyroid gland - piece of irregular brown tissue 27mm IME, 0.96g, Bisected. All In.

H&E 594515


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CD05 594509


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AE1/AE3 594510


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PAX8 594511


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ID240 594512


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Thyroglobulin 594513


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TTF1 Thyroid transcription factor 594516


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Case 10

Female 68 years

Presented in 2011 with a nodule in the left thyroid lobe. Initial FNA Thy3, Thy5. Underwent left hemithyroidectomy with completion right hemithyroidectomy and RAI.

H&E 594514


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