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EQA

British Neuropathological Society EQA scheme Circulation 56






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Circulation 56 - Case 1

Male 32 years

Right frontotemporal lesion. Cerebral tissue, 65x50x35mm. Sections show focal loss of demarcation between cortical grey matter and underlying white matter.


H&E


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IDH1 R132H


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ATRX


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Circulation 56 - Case 2

Female 55 years

Spinal intradural intramedullary lesion. Nodular tan tissue 24x11x10mm.


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Circulation 56 - Case 3

Male 33 years

Right cerebellar lesion. Nodular haemorrhagic tissue, measures 12x7x4mm. Bisected.


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Circulation 56 - Case 4

Male 63 years

Third ventricular cyst. Smooth surfaced cream tissue 20x12x10mm.


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Circulation 56 - Case 5

Male 69 years

Right frontal tumour. Nodular tissue 51x33x30mm.


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Circulation 56 - Case 6

Male 84 years

Left tempero-occipital tumour. Firm tissue measuring 25x17x12mm. IHC: IDH1 R132H negative, ATRX retained.


Circulation 56 - Case 7

Male 38 years

Intradural tumour L1-L3. Smooth surfaced grey and haemorrhagic tissue 40x15x15mm.


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Circulation 56 - Case 8

Male 68 years

Endoscopic decompression of pituitary lesion. Multiple haemorrhagic fragments up to 15mm. IHC: LH, FSH, growth hormone, ACTH and TSH negative.


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Prolactin


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Circulation 56 - Case 9

Female 7 years

Resection of third ventricular tumour. Multiple cream and haemorrhagic fragments up to 15mm.


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Circulation 56 - Case 10

Male 32 years

Epilepsy, left frontal craniotomy and lesionectomy. Cerebral tissue 35x23x23mm. Sections show focal loss of demarcation between grey matter and underlying white matter.


H&E


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Circulation 56 - Case 11

Female 35 years

Left cingulate ring enhancing lesion. Multiple cream coloured tissue cores, aggregate up to 14mm.


Circulation 56 - Case 12

Female 49 years

Right temporal biopsy, diffuse subcortical imaging change. Multiple grey fragments up to 17mm in aggregate.


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