Female 86 years

Red swollen left index finger discharging white chalky material. X-ray appearances of chronic osteomyelitis. Phalanx destroyed.

Macroscopic description:
Muliple fragments of brown tissue measuring 1.5 cm in aggregate.

Female 78 years

Cyst right eye - lateral canthus.

Macroscopic description:
1.3 cm skin wedge. Not cystic on cut section.

Male 69 years

Past history of G2 TCC and BCG induced bladder TB. At cystoscopy areas looking like cancer at bladder neck - biopsied.

Macroscopic description:
Tissue fragments weighing 1.4g.

Female 59 years

Rectal polyp discovered on barium meal. Received a smooth surface polyp 1.4 x 1 x 1cm.

Female 59 years

Fatty lump left temporal area. Skin and subcutaneous tissue 1.1 x 0.8 x 0.4cm.

Female 48 years

Growing congenital naevus, central back with the clinical diagnosis of malignant melanoma. An ellipse of skin 3.5 x 1.2 cm.

Male 68 years

Developed acute myeloid leukaemia. Treated. Suddenly developed features of peritonitis. A segment of grangrenous small intestine was removed.

Female 75 years

Six to eight week history of enlarged right occipital node. ?Lymphoma ?SCC ?TB. (The lymphoid cells in the infiltrate are CD20, CD79a, CD5, CD43 and CD23 positive).

Male 47 years

Cervical lymph node biopsy. Scattered large cells are positive for Ber H2 (CD30) and LeuM1 (CD15).

Male 49 years

Tonsillectomy. Section is of the left tonsil.

Male 73 years

Right adrenal mass seen on ultrasound in a patient with previous TCC bladder. Initial needle biopsy was performed and a diagnosis was suggested. Patient was investigated further and the adrenal was removed. Gland weighed 25g. Cut surface showed a well defined unencapsulated mass 30 mm across. Synaptophysin, chromogranin and NSE are positive. Occasional scattered cells show positive nuclear staining for S100 protein. Negative cytokeratin and epithelial membrane antigen.

Female 47 years

Pelvic mass. At laparotomy a diagnosis of left ovarian cancer with multiple peritoneal seedlings was made. The ovarian mass and a peritoneal biopsy were sent. Patient admitted to HDU in very poor state. Received an ill-defined mass 55 x 50 x 25mm with a yellow grey necrotic cut surface with adherent distorted fallopian tube. Representative section of mass

Male 77 years

Recurrent left hydrocele. Hard testis. Left orchidectomy to exclude neoplasm. Macroscopically a partly cystic partly solid lesion was identified infiltrating tunica and epididymis.

Female 76 years

Bladder biopsy. Patient had previous carcinoma of bladder. Lesional cells are strongly positive for CAM5.2, CK7 and show focal positivity for 34BE12 and focal intracytoplasmic mucin with D-PAS. LCA(CD45), CD79a, CD3 and CK20 were negative. Light chains showed some background staining, probably negative in tumour cells.

Male 92 years

Urine retention with mass on per-rectal examination. Biopsy from tumour, lower rectum 1.2 x 0.5cm.

Male 58 years

Known myeloma. Had chemotherapy and autologous bone marrow transplant. Multiple subcutaneous nodules all over body for three weeks ? Kaposi's sarcoma.

Macroscopic description:
A skin ellipse measuring 2 x 0.4cm with subcutaneous tissue to a depth of 1.3cm. On sectioning, there was a firm light brown area measuring 1.2cm within the subcutaneous tissue.

Immunohistochemistry:
CD79a positive, S100 negative.