Female 34 years

CT proven appendicitis.

Specimen: Appendicectomy.

Special stains/IHC results:
None.

Male 71 years

Right thyroid lump.

Specimen: Right thyroidectomy.

Special stains/IHC results:
CD56 +ve, synaptophysin +ve, CEA +ve, TTF1 +ve.

Female 75 years

Axillary lymphadenopathy.

Specimen: Core biopsy.

Special stains/IHC results:
BCL-6-, CD10-, CD20-, CD23-, CD3-, CD30+, CD5-, CD79-, IRF4+, LMP-1+>.

Male 75 years

Scalp lesion. History of kidney resection for cancer.

Specimen: Excision biopsy.

Special stains/IHC results:
Positive for PAX 8, CD10 and CAIX.

Male 82 years

Scrotal lesion.

Specimen: Excision.

Special stains/IHC results:
Positive for AE1/3, CK20, CK7, 34BE12, p40 and GATA3; negative for GCDFP15.

Female 60 years

Skin lesion.

Specimen: Excision.

Special stains/IHC results:
Large cells positive for S100, CD68 and OCT2; negative for Melan-A, SOX10, HMB-45.

Female 68 years

Suspicious liver lesion at elective cholecystectomy. History of breast carcinoma.

Specimen: Liver biopsy.

Special stains/IHC results:
None.

Male 86 years

? SCC central back.

Specimen: Pigmented ulcerated skin nodule 25 mm maximum.

Special stains/IHC results:
None.

Female 69 years

Vaginal prolapse.

Specimen: Hysterectomy including polyp 10 mm maximum.

Special stains/IHC results:
None.

Female 53 years

2 cm GIST in greater curve.

Specimen: Mucosal tissue 100 x 80 x 5 mm with nodule 20 mm.

Special stains/IHC results:
S100+, AE1/AE3-.

Female 28 years

Tail of parotid lump.

Specimen: Salivary gland 35 x 22 x 20 mm with firm nodule 23 mm.

Special stains/IHC results:
None.

Male 53 years

Radical left nephrectomy for large tumour. No adrenal gland received.

Specimen: A circumscribed nodule in hilar fat.

Special stains/IHC results:
Cells positive with melan A and inhibin, negative with CAIX.

Female 41 years

Pelvic mass.

Specimen: Core biopsy.

Special stains/IHC results:
SMA focally +ve, B-catenin +ve, MIB 2%.

Female 50 years

Fibroid ? sarcoma.

Specimen: THBSO. Section from lesion and adjacent myometrium.

Special stains/IHC results:
None provided.

Female 74 years

U4 nodule.

Specimen: Hemithyroidectomy.

Special stains/IHC results:
None provided.

Female 74 years

Right canthus tumour involving upper and lower eyelids.

Specimen: Biopsy - 4 pale brown pieces of skin, largest 2 x 2 x 2 mm and smallest 1 x 1 x 1 mm.

Special stains/IHC results:

AB-PASD: intracytoplasmic stromal mucin +
CK7: patchy tumour cell staining
BerEp4: strong tumour staining
ER: strong positive
CD56 and synaptophysin: patchy strong staining
Lesional cells negative for: Sox10, S100, Melan A, CK20, p63.