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EQA

North West EQA - Circulation AX 2017






   

Case AX1 Category A (scoring)

Female 72 years

TURB, Bladder tumour chips "2g of multiple pale brown tissue fragments overall 30mm". Special stains: None


H&E 370488


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Case AX2 Category A (scoring)

Female 57 years

Excision of lesion left lateral foot "? Cream cyst measuring 13mm." Special stains: Lesional cells, SMA, Desmin positive.


H&E 370489


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Case AX3 Category A (scoring)

Male 46 years

Left superficial parotidectomy for mass lesion "brown tissue 68x47x23mm with solid brown nodule in the centre 20x12x8mm." Special stains: None.


H&E 370490


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Case AX4 Category A (scoring)

Male 58 years

Left arm epidermal cyst "skin sample 25x10x20mm with grey tumour." Special stains: CK20 positive. CD56 positive. Synaptophysin positive. LCA negative.


H&E 370491


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Case AX5 Category A (scoring)

Male 79 years

Swelling right hand "firm grey nodules, partially cystic." Special stains: None.


H&E 370492


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Case AX6 Category A (scoring)

Female 55 years

L knee "loose body from left knee." Special stains: None.


H&E 370493


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Case AX7 Category A (scoring)

Male 19 years

Multiple long standing small lumps in the scrotal skin. IMP subaceous cyst ? lipoma "scrotum: ellipse of skin measuring 11x6mm with underlying tissue to a depth of 3mm. On cut surface there is a well-defined pale cyst measuring 5mm in maximum diameter and contains light soft material." Special stains: None.


H&E 370494


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Case AX8 Category A (scoring)

Female 81 years

TURBT of bladder lesions at left lateral wall and bladder trigone "bladder biopsies TURBT: 3 biopsies larger 8mm." Special stains: Congo red positive.


H&E 370495


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Case AX9 Category A (scoring)

Female 62 years

? RCC left kidney "Left kidney: Size of the kidney with tumour 60x90x55mm (nephrectomy) the actual kidney size is 100x60x55mm. weight 451g, Location of tumour: middle zone. Size of tumour: 40x33x35mm, yellow with areas of haemorrhage. Ureter: 70mm long. Adrenal attached: No. Lymph nodes: No. Invasion beyond capsule: No. Invasion beyond gerota's fascia: no. Appearance of pelvicalyceal: normal. Abnormalities of renal parenchyma: no. Tumour in renal vein: no. Lymph nodes found: no." Special stains: None.


H&E 370496


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Case AX10 Category A (scoring)

Female 19 years

Pregnancy tissue HHCG >100,000 "received 336.3g of placental and decidual tissue." Special stains: p57 +ve in decidua / -ve in chorionic villi.


H&E 370497


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Case AX11 Category A (scoring)

Female 51 years

Pearly papule on left forehead increased in size over two years "14x8x3mm. The surface bears a pale pearly papule measuring 5x4mm." Special stains: None.


H&E 370498


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Case AX12 Category A (scoring)

Male 73 years

Generalised lymphadenopathy, mainly abdominal and inguinal "lymph node measuring 36x16x14mm." Special stains: Pale cells +ve for CD163, CD1a, S100 & Langerin (+/-) / -ve for PU1.


H&E 370499


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Case AX13 Category B (non-scoring educational)

Female 62 years

Excision of lump right upper quadrant of abdomen "ellipse of skin 70x25mm with soft tissue 85x50x30mm showing a diffuse firm area with possible focal necrosis 70x30x30mm." Special stains: None in house. Referred for second opinion: Lesional cells, S100, CD68, CD163 positive. Lymphocytes mixed T and B cells.


H&E 370500


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Case AX14 Category B (non-scoring educational)

Male 82 years

Fracture neck of femur, history of CA bladder "femur head." Special stains: CK7 positive, 34βE12 positive, CK20 negative, PSA negative, TTF1 negative, NapsinA negative.


H&E 370501


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Case AX15 Category B (non-scoring educational)

Male 67 years

Laparoscopic radical right nephrectomy performed for renal tumour, "Right kidney: Size of the kidney with tumour: 150x80x50mm (nephrectomy - the actual size of the kidney measuring 100x80x50mm). Weight: 325.9g. Location of tumour: Lower pole. Size of tumour and appearance: 25x20mm dark brown and solid/cystic. Ureter: 70mm long. Adrenal attached: No. Lymph nodes: Not found. Invasion beyong capsule: no. Invasion beyong Gerota's fascia: No. Appearance of pelvicalyceal: prominent dilatation. Abnormalities of renal parenchyma: signs of atrophy. Renal vein appearance: Free from tumour. Lymph nodes found: No" Special stains: CD117 positive, CD15 (patchy), CK7 occasional cells. Vimentin, CK20 and AMCAR negative.


H&E 370502


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Case AX16 Category B (non-scoring educational)

Male 24 years

Previous classical hodgkins lymphoma treated by allogeneic stem cell transplant. Now persistent sore throat and PET positive left tonsil ? recurrence. "two fragments of grey brown tissue 9mm and 11mm in maximum dimension." Special stains: Large atypical cells +ve for BCL-6, CD79a, CD20, IRF4, OCT-2, CD30, PAX-5 & LMP-1 (+/-) / -ve for CD15.


H&E 370503


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