Female 49 years

TVA 15cm rectosigmoid - anterior resection.

Gross description:
upper rectum/distal sigmoid, 150mm long. Sessile polyp 37mm max diam present on anterior wall, 30mm from distal margin. Section taken from polyp and underlying bowel.

Immunohistochemistry:
Surface epithelium: positive for CDX-2 and CK20; negative for CK7 and ER; Glands within bowel wall: epithelium positive for ER & CK7, negative for CDX-2 and CK20; surrounding stroma positive for ER and CD10.

Male 67 years

2 week history of keratotic nodule on lower back. ?BCC.

Gross description:
skin ellipse 45 x 19 x 5mm deep bearing a central pale raised nodule 11 x 9 x 4mm high.

Male 57 years

Gl 4+3 CaP. PSA 9.2ng/ml.

Gross description:
radical prostatectomy specimen, including parts of the seminal vesicles, the prostate weighing 35g.

Female 30 years

Gastric antral lesion.

Female 48 years

Lung biopsy for ground glass shadows. Heavy e-cigarette user.

Special stains/IHC results:
S100 & CD1a positive in lesions.

Female 68 years

Multiple lung nodules.

Special stains/IHC results:
AE1/AE3, pax-8 & CD10 positive. CK7 negative.

Male 48 years

Cyst right arm.

Female 60 years

Unilateral nasal swelling.

Macroscopic description:
grey oedematous polypoid pieces tissue measuring up to 2.5cm.

Female 23 years

Incisional biopsy to rash left arm.

Special stains/IHC results:
disrupted fibres in mid dermis highlighted by EVG and Von Kossa.

Male 23 years

Epidermal cyst in scrotum.

Female 48 years

Right nipple wedge biopsy ? Paget's disease. Known right LIQ carcinoma.

Female 33 years

Previous ruptured IPP implants right axillary node.

Female 44 years

Breast lump. Previous FNA: C4. Previous core biopsy: B3/B4, ?malignant phyllodes tumour.

Current specimen:
wide local excision breast lump weighing 35g, containing a well-circumscribed lesion about 15mm diameter.

Male 60 years

Nodule RUL of lung.

Female 82 years

Small bowel resection. PUO 3/52. Free air on CT. Ten small bowel perforations. Normal arterial supply. ?vasculitic process ? lymphoma.

Macroscopic description:
multiple well defined perforations with associated mucosal ulceration. Bowel in between perforations appeared normal.

Female 71 years

Left ovarian solid mass ? metastatic disease. Previous mastectomy one year ago.

Special stains/IHC results:
EMA, ER and GCDFP positive. PR negative.