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EQA

East Midlands EQA - Circulation I 2012






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Case I819

Male 69 years

Solid lesion middle of right kidney, radiologically renal cancer.

Specimen: Right kidney.

Macroscopic description:
Right kidney - nephrectomy specimen. Kidney itself measures 95 x 50 x 34 mm. Shows a yellow-grey rounded tumour 32 mm diameter centrally.






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Case I820

Female 83 years

Complex ovarian mass, adherent to peritoneum.

Specimen: Total hysterectomy.

Macroscopic description:
Collapsed cyst 400 mm across with solid area 100 x 70 x 40 mm. Part of solid lesion shows haemorrhagic infarction. Cyst contains blood clots.

Immunohistochemistry:
Inhibin, calretinin, WT1, Vimentin, SMA, AE1/3, CD56 all positive. EMA and CD10 negative.






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Case I821

Female 38 years

Left laparoscopic adrenalectomy.

Specimen: Left adrenalectomy.

Macroscopic description:
Adrenal gland with attached tumour. Adrenal gland is separate from tumour. Tumour measures 100 x 60 x 50 mm. On slicing shows greyish white, whorled and myxoid areas.






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Case I822

Male 75 years

Mediastinal lymphadenopathy.

Specimen: Lymph node.

Macroscopic description:
Multiple pieces of lymph nodes.






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Case I823

Female 28 years

Distal ileum abnormality.

Specimen: Right hemicolectomy.

Macroscopic description:
Right hemicolectomy - apart from ileal ulcers, the large bowel shows an ill defined slightly haemorrhagic nodule 1.5 cm x 3 cm.






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Case I824

Male 33 years

Anal fissure and piles.

Specimen: Sentinel pile.

Macroscopic description:
Three grey polypoid tissue fragments, largest 18 x 12 x 5 mm.






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Case I825

Female 90 years

Gastric haemorrhage.

Specimen: Gastric tumour excision.

Macroscopic description:
Gastric wall 40 x 30 x 20 mm containing submucosal neoplasm 25 mm in max extent.

Immunohistochemistry:
SMA, Vimentin, CD34, CD117, DOG1: Positive S100, NSE, Desmin: negative.






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Case I826

Female 47 years

Cystic show growing swelling - impression: subcutaneous cyst excised completely.

Specimen: Skin excision right leg.

Macroscopic description:
Smooth pale firm nodule measuring 12 x 8 x 5 mm. Specimen is bisected.

Immunohistochemistry:
Negative - CD34, factor 13A, S100, CK, AE1/AE3, positive - SMA, desmin.






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Case I827

Female 64 years

Picked up by bowel cancer screening programme.

Specimen: Polyp from sigmoid colon.

Macroscopic description:
A polyp 22 x 16 x 10 mm. No stalk.






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Case I828

Female 35 years

HIV positive.

Specimen: Urinary bladder biopsy.

Macroscopic description:
Bladder biopsies, number of pieces 2.






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Case I829

Female 65 years

Tumour in mesocolon.

Specimen: Large bowel resection.

Macroscopic description:
200 mm of colon. Smooth mass in mesentery 110 x 65 x 60 mm. Cut surface grey and fleshy.

Immunohistochemistry:
Positive SMA, Des, Negative CD117






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Case I830

Male 72 years

Thickening of right olecranon bursa with nodules.

Specimen: Olecranon bursa.

Macroscopic description:
Yellow/white cystic nodule measuring 60 x 42 x 30 mm. Cut surface is chalky white in appearance.






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